Próteses odontológicas associadas a Nanopartículas de Prata biogênicas: caracterização e atividade antimicrobiana

Abstract

Introduction: The increased need for dental prostheses means that the implications of this treatment are the focus of many clinical and scientific discussions today. Poorly adapted and traumatogenic prostheses can be the main etiological factor of many diseases of the oral cavity. Given this, it is necessary, in addition to stimulating hygiene, to explore and develop new technologies to make PMMA antimicrobial. Biogenic AgNPs as a surface treatment for acrylic resin is one of the disruptive and innovative ways to make a prosthesis antimicrobial. Objective: the present study carried out the characterization, antimicrobial activity, durability determination, and roughness analysis of PMMA specimens treated with biogenic AgNP. Material and methods: The specimens were treated with a biogenic AgNP solution synthesized by the fungus fusarium oxysporum in different treatment groups, and then the physicochemical characteristics of the Nanoparticle, performance, sensitivity test to bacteria, thermal cycling, and contact test were proven. Modified direct, color evaluation through spectrophotometry testing and roughness testing. Results: The resins that received nanoparticles in the total mass did not show antimicrobial activity, despite the incorporation of AgNP significantly improving the surface roughness of the colorless resin. The other surface treatments showed high antibacterial activity and moderate antifungal activity. AgNP was not able to cause clinically significant color changes, it only showed a decrease in red saturation in the pink resin. Conclusion: Surface treatments with AgNP on thermopolymerizable acrylic resin can resist up to 30 days in the oral cavity, do not change the color or roughness of the material, and have high antimicrobial activity. More studies need to be carried out to determine the activity over longer periods, more challenging situations, and with other NPM species.