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Campo DCValorIdioma
dc.creatorSantos, Mateus Leite-
dc.date.accessioned2025-01-14T12:15:47Z-
dc.date.available2025-01-12-
dc.date.available2025-01-14T12:15:47Z-
dc.date.issued2024-12-21-
dc.identifier.citationSANTOS, Mateus Leite. Próteses odontológicas associadas a nanopartículas de prata biogênicas: caracterização e atividade antimicrobiana. Orientadora: Ana Rita Sokolonski Antón. 2024. 60 f. Dissertação (Mestrado em Processos Interativos de Órgãos e Sistemas) - Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, 2024.pt_BR
dc.identifier.urihttps://repositorio.ufba.br/handle/ri/40895-
dc.description.abstractIntroduction: The increased need for dental prostheses means that the implications of this treatment are the focus of many clinical and scientific discussions today. Poorly adapted and traumatogenic prostheses can be the main etiological factor of many diseases of the oral cavity. Given this, it is necessary, in addition to stimulating hygiene, to explore and develop new technologies to make PMMA antimicrobial. Biogenic AgNPs as a surface treatment for acrylic resin is one of the disruptive and innovative ways to make a prosthesis antimicrobial. Objective: the present study carried out the characterization, antimicrobial activity, durability determination, and roughness analysis of PMMA specimens treated with biogenic AgNP. Material and methods: The specimens were treated with a biogenic AgNP solution synthesized by the fungus fusarium oxysporum in different treatment groups, and then the physicochemical characteristics of the Nanoparticle, performance, sensitivity test to bacteria, thermal cycling, and contact test were proven. Modified direct, color evaluation through spectrophotometry testing and roughness testing. Results: The resins that received nanoparticles in the total mass did not show antimicrobial activity, despite the incorporation of AgNP significantly improving the surface roughness of the colorless resin. The other surface treatments showed high antibacterial activity and moderate antifungal activity. AgNP was not able to cause clinically significant color changes, it only showed a decrease in red saturation in the pink resin. Conclusion: Surface treatments with AgNP on thermopolymerizable acrylic resin can resist up to 30 days in the oral cavity, do not change the color or roughness of the material, and have high antimicrobial activity. More studies need to be carried out to determine the activity over longer periods, more challenging situations, and with other NPM species.pt_BR
dc.description.sponsorshipCapes - Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageporpt_BR
dc.publisherUniversidade Federal da Bahiapt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectNanotecnologiapt_BR
dc.subjectNanopartículas metálicaspt_BR
dc.subjectPrótese dentáriapt_BR
dc.subjectMateriais dentáriospt_BR
dc.subjectMateriais biomédicos e odontológicospt_BR
dc.subject.otherNanotechnologypt_BR
dc.subject.otherMetal Nanoparticlespt_BR
dc.subject.otherDental Prosthesispt_BR
dc.subject.otherDental Materialspt_BR
dc.subject.otherBiomedical and Dental Materialspt_BR
dc.titlePróteses odontológicas associadas a Nanopartículas de Prata biogênicas: caracterização e atividade antimicrobianapt_BR
dc.title.alternativeDental prostheses pssociated with biogenic silver Nanoparticles: characterization and antimicrobial activitypt_BR
dc.typeDissertaçãopt_BR
dc.publisher.programPrograma de Pós-Graduação em Processos Interativos dos Órgãos e Sistemas (PPGORGSISTEM) pt_BR
dc.publisher.initialsUFBApt_BR
dc.publisher.countryBrasilpt_BR
dc.subject.cnpqCNPQ::CIENCIAS BIOLOGICAS::MICROBIOLOGIApt_BR
dc.subject.cnpqCNPQ::CIENCIAS DA SAUDE::ODONTOLOGIApt_BR
dc.contributor.advisor1Antón, Ana Rita Sokolonski-
dc.contributor.advisor1IDhttps://orcid.org/0000-0001-8089-4128pt_BR
dc.contributor.advisor1Latteshttp://lattes.cnpq.br/1228384941765961pt_BR
dc.contributor.referee1Antón, Ana Rita Sokolonski-
dc.contributor.referee1IDhttps://orcid.org/0000-0001-8089-4128pt_BR
dc.contributor.referee1Latteshttp://lattes.cnpq.br/1228384941765961pt_BR
dc.contributor.referee2Lira, Andréa Fabiana de-
dc.contributor.referee2IDhttps://orcid.org/0000-0003-3945-2613pt_BR
dc.contributor.referee2Latteshttp://lattes.cnpq.br/1727445128048492pt_BR
dc.contributor.referee3Gabler, Ilanna Guimarães-
dc.contributor.referee3Latteshttp://lattes.cnpq.br/1670478079353578pt_BR
dc.creator.IDhttps://orcid.org/0009-0003-0504-7043pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/5347295247563620pt_BR
dc.description.resumoIntrodução: O aumento da necessidade pelo uso de próteses dentárias faz com que as implicações deste tratamento estejam sobre o foco de muitas discussões clínicas e científicas na atualidade. Próteses mal adaptadas e traumatogênicas podem ser o fator etiológico principal de muitas enfermidades da cavidade oral. Diante disso, é necessário além de estimular a higiene, a exploração e desenvolvimento de novas tecnologias para tornar o PMMA antimicrobiano. O uso de AgNP biogênicas como tratamento de superfície da resina acrílica é uma das formas disruptivas e inovadoras de tornar uma prótese antimicrobiana. Objetivo: o presente estudo realizou a caracterização, atividade antimicrobiana, determinação da durabilidade e análise da rugosidade de corpos de prova de PMMA tratados com AgNP biogênicas. Material e métodos: Os espécimes confeccionados em resina acrílica temropolimerizável foram tratados com uma solução de AgNP biogênica sintetizada pelo fungo fusarium oxysporum em diferentes grupos de tratamento, em seguida foram analisadas as características físico-químicas da Nanopartícula, realizando teste de sensibilidade a antibióticos, ciclagem térmica, teste de contato direto modificado, avaliação de cor através de ensaio de espectofotometria e ensaio de rugosidade. Resultados: Os espécimes de resinas que receberam nanopartículas na massa total não apresentaram atividade antimicrobiana, apesar da incorporação de AgNP melhorar significativamente a rugosidade superficial da resina incolor. Os demais tratamentos de superfície apresentaram alta atividade antibacteriana e moderada atividade antifúngica. AgNP não foi capaz de provocar alterações de cor clinicamente significativas, apresentou apenas diminuição da saturação de vermelho na resina rosa. Conclusão: Os tratamentos de superfície com AgNP em resina acrílica termopolimerizável podem resistir até 30 dias na cavidade oral, não alteram a cor ou a rugosidade do material e apresentam alta atividade antimicrobiana, mais estudos precisam ser realizados para a determinação da atividade em períodos mais longos, situações mais desafiadoras e com outras espécies de NPM.pt_BR
dc.publisher.departmentInstituto de Ciências da Saúde - ICSpt_BR
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