Por favor, use este identificador para citar o enlazar este ítem:
https://repositorio.ufba.br/handle/ri/17078
metadata.dc.type: | Artigo de Periódico |
Título : | Estimation of Biodiesel Cytotoxicity by Using Acid Phosphatase as a Biomarker of Lysosomal Integrity |
Otros títulos : | Bulletin of Environmental Contamination and Toxicology |
Autor : | Cruz, Andréa Cristina Santos da Leite, Maria Bernadete Neiva Lemos Rodrigues, Luiz Erlon Araújo Nascimento, Iracema Andrade |
metadata.dc.creator: | Cruz, Andréa Cristina Santos da Leite, Maria Bernadete Neiva Lemos Rodrigues, Luiz Erlon Araújo Nascimento, Iracema Andrade |
Resumen : | Biodiesel is promoted as environmentally less harmful than diesel fuel. Nevertheless its water-soluble-fraction (WSF) may contain methanol, which appears by a reversion of the transesterification reaction, when biodiesel contacts water. This paper evaluated the loss of the lysosomal membrane integrity in liver homogenate of juvenils Tilapia exposed to biodiesels-WSF, through the increase of the acid phosphatase activity, as an evidence of citotoxicity. Differences in the enzyme activity levels (3.4, 2.3 and 0.8 mU mg−1 total protein over the control value, which was 1.6 mU mg−1 total protein), found for castor oil, waste cooking-oil and palm oil-biodiesels, respectively, were indicative of their toxicity according to this decreasing trend. WSF-chromatograms suggest the cytotoxicity as related to methanol. |
Palabras clave : | Biodiesel Hepatotoxicity Lysosomal biomarker Acid phosphatase |
metadata.dc.rights: | Acesso Aberto |
URI : | http://repositorio.ufba.br/ri/handle/ri/17078 |
Fecha de publicación : | 2012 |
Aparece en las colecciones: | Artigo Publicado em Periódico (LABIOMAR) |
Ficheros en este ítem:
No hay ficheros asociados a este ítem.
Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.