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https://repositorio.ufba.br/handle/ri/16348
metadata.dc.type: | Artigo de Periódico |
Title: | Severe periodontitis is associated with diastolic blood pressure elevation in individuals with heterozygous familial hypercholesterolemia: a pilot study |
Other Titles: | Journal of Periodontology |
Authors: | Vieira, Carolina L. Z. Cury, Patricia Ramos Miname, Marcio H. Martinez, Lilton R. Bortolotto, Luiz Aparecido Giuliano, Isabela B. Santos, Raul D. Caramelli, Bruno |
metadata.dc.creator: | Vieira, Carolina L. Z. Cury, Patricia Ramos Miname, Marcio H. Martinez, Lilton R. Bortolotto, Luiz Aparecido Giuliano, Isabela B. Santos, Raul D. Caramelli, Bruno |
Abstract: | Background: This pilot study evaluates the association of severe periodontitis with pulse wave velocity (PWV), carotid artery intima-medial thickness (IMT), and clinical, metabolic, and atherogenic inflammatory markers in 79 subjects with heterozygous familial hypercholesterolemia (hFH). All subjects were free of previous vascular disease manifestations. Methods: The body mass index (in kilograms per square meter), plasma lipids, glucose, C-reactive protein, and white blood cell counts were evaluated. After full-mouth periodontal examinations, patients were categorized into the severe periodontitis group (SPG) or non-severe periodontitis group (NSPG). Results: The SPG showed significantly higher values of cholesterol-year scores, triglycerides, glucose, PWV, IMT, and diastolic blood pressure (DBP) (P ≤0.05) than the NSPG. After adjustment for traditional risk factors for atherosclerosis, only the association between severe periodontitis and DBP (odds ratio: 3.1; 95% CI: 1.1 to 8.5; P = 0.03) was confirmed. Conclusion: In individuals with hFH, severe periodontitis was associated with a higher DBP, which suggests that severe periodontitis, itself, may contribute to the increased cardiovascular risk profile in this population. |
Keywords: | Carotid artery diseases Hypercholesterolemia Inflammation Periodontal disease Risk factors |
metadata.dc.publisher.country: | Brasil |
metadata.dc.rights: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/16348 |
Issue Date: | 2011 |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Odontologia) |
Files in This Item:
File | Description | Size | Format | |
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Patricia R. Cury.pdf | 503,09 kB | Adobe PDF | View/Open |
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