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Use este identificador para citar ou linkar para este item: https://repositorio.ufba.br/handle/ri/16348
Tipo: Artigo de Periódico
Título: Severe periodontitis is associated with diastolic blood pressure elevation in individuals with heterozygous familial hypercholesterolemia: a pilot study
Título(s) alternativo(s): Journal of Periodontology
Autor(es): Vieira, Carolina L. Z.
Cury, Patricia Ramos
Miname, Marcio H.
Martinez, Lilton R.
Bortolotto, Luiz Aparecido
Giuliano, Isabela B.
Santos, Raul D.
Caramelli, Bruno
Autor(es): Vieira, Carolina L. Z.
Cury, Patricia Ramos
Miname, Marcio H.
Martinez, Lilton R.
Bortolotto, Luiz Aparecido
Giuliano, Isabela B.
Santos, Raul D.
Caramelli, Bruno
Abstract: Background: This pilot study evaluates the association of severe periodontitis with pulse wave velocity (PWV), carotid artery intima-medial thickness (IMT), and clinical, metabolic, and atherogenic inflammatory markers in 79 subjects with heterozygous familial hypercholesterolemia (hFH). All subjects were free of previous vascular disease manifestations. Methods: The body mass index (in kilograms per square meter), plasma lipids, glucose, C-reactive protein, and white blood cell counts were evaluated. After full-mouth periodontal examinations, patients were categorized into the severe periodontitis group (SPG) or non-severe periodontitis group (NSPG). Results: The SPG showed significantly higher values of cholesterol-year scores, triglycerides, glucose, PWV, IMT, and diastolic blood pressure (DBP) (P ≤0.05) than the NSPG. After adjustment for traditional risk factors for atherosclerosis, only the association between severe periodontitis and DBP (odds ratio: 3.1; 95% CI: 1.1 to 8.5; P = 0.03) was confirmed. Conclusion: In individuals with hFH, severe periodontitis was associated with a higher DBP, which suggests that severe periodontitis, itself, may contribute to the increased cardiovascular risk profile in this population.
Palavras-chave: Carotid artery diseases
Hypercholesterolemia
Inflammation
Periodontal disease
Risk factors
País: Brasil
Tipo de Acesso: Acesso Aberto
URI: http://repositorio.ufba.br/ri/handle/ri/16348
Data do documento: 2011
Aparece nas coleções:Artigo Publicado em Periódico (Faculdade de Odontologia)

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