Please use this identifier to cite or link to this item:
https://repositorio.ufba.br/handle/ri/7442
metadata.dc.type: | Artigo de Periódico |
Title: | A chemotherapy model for the treatment of cancer with metastasis |
Other Titles: | Mathematical and Computer Modelling |
Authors: | Pinho, Suani Tavares Rubim de Freedman, H. I. Nani, F. |
metadata.dc.creator: | Pinho, Suani Tavares Rubim de Freedman, H. I. Nani, F. |
Abstract: | In this paper, we propose and analyse a mathematical model of cancer treatment by chemotherapy where there is metastasis from a primary to a secondary site by the cancer cells. We view the interactions between normal and cancer cells as being competitive for available resources, and we think of the chemotherapy agent as a predator on both normal and cancer cells. The metastasis may be time delayed. The analysis is carried out both analytically (where possible) and numerically. In particular, we look at the existence and stability of equilibria of our model, which consists of six differential equations. As well, we investigate (numerically) the behavior of solutions for various values of the parameters. |
Keywords: | Competition models Chemotherapy Metastasis; Stability Time delay |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/7442 |
Issue Date: | Nov-2002 |
Appears in Collections: | Artigo Publicado em Periódico (FIS) |
Files in This Item:
File | Description | Size | Format | |
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1-s2.0-S0895717702002273-main.pdf Restricted Access | 3,02 MB | Adobe PDF | View/Open Request a copy |
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