Por favor, use este identificador para citar o enlazar este ítem:
https://repositorio.ufba.br/handle/ri/2890
metadata.dc.type: | Artigo de Periódico |
Título : | Hemoglobinopathies in newborns from Salvador, Bahia, Northeast Brazil |
Otros títulos : | Cadernos de Saúde Pública |
Autor : | Adorno, Elisângela Vitória Couto, Fábio David Moura Neto, José Pereira de Menezes, Joelma Figueiredo Rêgo, Marco Antônio Vasconcelos Reis, Mitermayer Galvão dos Gonçalves, Marilda Souza |
metadata.dc.creator: | Adorno, Elisângela Vitória Couto, Fábio David Moura Neto, José Pereira de Menezes, Joelma Figueiredo Rêgo, Marco Antônio Vasconcelos Reis, Mitermayer Galvão dos Gonçalves, Marilda Souza |
Resumen : | Hemoglobinopathies are hereditary disorders of the hemoglobin molecule with a high prevalence worldwide. Brazil has a prevalence of 0.1 to 0.3% of newborns with sickle cell anemia and 20.0 to 25.0% of heterozygous α2 thalassemia among African Brazilians. In the present study, we investigated the presence of variant emoglobins and α2 3.7 Kb and α2 4.2 Kb thalassemia in newborns from Salvador, Bahia, Brazil. Samples of umbilical cord blood from a total of 590 newborns were analyzed, of which 57 (9.8%) were FAS; 36 (6.5%) FAC; one (0.2%) SF; and five (0.9%) FSC. One hundred fourteen (22.2%) newborns had α2 3.7 Kb thalassemia, of whom 101 (19.7%) were heterozygous and 13 (2.5%) homozygous, showing statistical significance for hematological data between newborns with normal α genes and α2 3.7 Kb thalassemia carriers. The α2 4.2 Kb thalassemia was not found. Frequencies found in the present study confirm that hemoglobinopathies are a public health problem in Brazil, emphasizing the need for neonatal screening and genetic counseling programs. |
Palabras clave : | Hemoglobinopathies Sickle Cell Anemia Thalassemia Newborn Infant Hemoglobinopatias Anemia Falciforme Talassemia Recém-Nascido |
URI : | http://www.repositorio.ufba.br/ri/handle/ri/2890 |
Fecha de publicación : | 2005 |
Aparece en las colecciones: | Artigo Publicado em Periódico (FAR) |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
---|---|---|---|---|
32.pdf | 72,45 kB | Adobe PDF | Visualizar/Abrir |
Los ítems de DSpace están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.