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https://repositorio.ufba.br/handle/ri/17520
metadata.dc.type: | Artigo de Periódico |
Title: | Establishment and characterization of an oral mucosal melanoma cell line (MEMO) derived from a longstanding primary oral melanoma |
Other Titles: | American Journal of Dermatopathology |
Authors: | Lourenço, Silvia Vanessa Bologna, Sheyla Batista Hsieh, Ricardo Sangueza, Martin Fernandes, Juliana Dumet Nico, Marcello Menta Simonsen |
metadata.dc.creator: | Lourenço, Silvia Vanessa Bologna, Sheyla Batista Hsieh, Ricardo Sangueza, Martin Fernandes, Juliana Dumet Nico, Marcello Menta Simonsen |
Abstract: | Oral mucosal melanoma is rare. Its incidence peaks between 41 and 60 years of age; male/female ratio is 2:1. Preferred oral sites include hard palate and maxillary gingiva. Risk factors have not been clearly identified, but pigmented lesions may be present before the diagnosis of oral melanoma. We report an unusual case of oral mucosal melanoma of long-standing duration on hard palate and maxillary alveolar ridge in a male patient. Histopathologic features confirmed the diagnosis of invasive melanoma with a prominent in situ component. A cell lineage derived from the tumor was established and characterized, with phenotypic markers of melanocytes. |
Keywords: | Cell culture Melanoma Oral mucosa |
metadata.dc.rights: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/17520 |
Issue Date: | 2013 |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Files in This Item:
File | Description | Size | Format | |
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Silvia V. Lourenço.pdf | 430,21 kB | Adobe PDF | View/Open |
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