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https://repositorio.ufba.br/handle/ri/14473
metadata.dc.type: | Artigo de Periódico |
Title: | Antimicrobial activity and structural study of disubstituted Thiourea Derivatives |
Other Titles: | Chemical Monthly / Monatshefte für Chemie |
Authors: | Cunha, Silvio do Desterro Macedo Junior, Fernando César de Costa, Giselle A. Nobre Rodrigues Junior, Manoel T. Verde, Rosival B. V. Souza Neta, Lourdes Cardoso de Vencato, Ivo Lariucci, Carlito Sá, Fernando P. |
metadata.dc.creator: | Cunha, Silvio do Desterro Macedo Junior, Fernando César de Costa, Giselle A. Nobre Rodrigues Junior, Manoel T. Verde, Rosival B. V. Souza Neta, Lourdes Cardoso de Vencato, Ivo Lariucci, Carlito Sá, Fernando P. |
Abstract: | The antimicrobial activity of six N-phenyl- and fourteen N-benzoylthiourea derivatives were evaluated from their Minimal Inhibitory Concentration (MIC) values using the microdilution procedure against ten microorganisms. Most of the compounds exhibited selective activity against fungi and Gram-positive bacteria, which were very effectively inhibited by some of the tested thioureas. Additionally, SAR considerations and four novel X-ray diffraction structures of N-benzoylthioureas are included. |
Keywords: | Benzoylthioureas Phenylthioureas X-ray structure |
metadata.dc.rights: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/14473 |
Issue Date: | 2007 |
Appears in Collections: | Artigo Publicado em Periódico (Química) |
Files in This Item:
File | Description | Size | Format | |
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art%3A10.1007%2Fs00706-007-0600-y.pdf | 200,62 kB | Adobe PDF | View/Open |
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