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https://repositorio.ufba.br/handle/ri/14356| metadata.dc.type: | Artigo de Periódico |
| Title: | Long lasting BCG protection against leprosy |
| Other Titles: | Vaccine |
| Authors: | Rodrigues, Laura Cunha Kerr, Ligia Regina Franco Sansigolo Frietas, Max Victor Carioca Barreto, Mauricio Lima |
| metadata.dc.creator: | Rodrigues, Laura Cunha Kerr, Ligia Regina Franco Sansigolo Frietas, Max Victor Carioca Barreto, Mauricio Lima |
| Abstract: | Background: BCG vaccine protects against leprosy. Objectives: Estimate BCG protection against leprosy by age by age. Methods: A case control study with 226 cases of leprosy and 857 controls. BCG vaccination was ascertained via examination of BCG scars. Protection is presented for three age groups. Results: BCG protection against leprosy was 86% (95% CI: 77–92%) in the age group 18–29; 54% (95% CI: −37% to 85%) in the age group 30–39 and 32% (95% CI: −3% to 56%) in those aged 40 or more. Conclusions: BCG efficacy against leprosy may well last for three decades and possibly even longer. BCG vaccination must have contributed to worldwide reduction in leprosy incidence. |
| Keywords: | BCG vaccine Leprosy Waning of protection Duration of protection Vaccine efficacy |
| metadata.dc.rights: | Acesso Aberto |
| URI: | http://repositorio.ufba.br/ri/handle/ri/14356 |
| Issue Date: | 2007 |
| Appears in Collections: | Artigo Publicado em Periódico Estrangeiro (ISC) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 1-s2.0-S0264410X07008365-main.pdf | 96,86 kB | Adobe PDF | View/Open |
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