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metadata.dc.type: | Artigo de Periódico |
Title: | Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load |
Other Titles: | Journal of Medical Virology |
Authors: | Almeida, Herbert Vitvitski, Ludmila Carmo, Theomira Mauadie Azevedo Paraná, Raymundo Reis, Mitermayer Galvão dos |
metadata.dc.creator: | Almeida, Herbert Vitvitski, Ludmila Carmo, Theomira Mauadie Azevedo Paraná, Raymundo Reis, Mitermayer Galvão dos |
Abstract: | Hepatitis C is a worldwide public health problem and its transmission is clearly associated with the parenteral route, however, the virus has also been isolated from other body fluids. Hepatitis C virus (HCV) RNA has been detected in saliva, yet the relationship between HCV and oral pathology is not clearly understood. Therefore, an investigation on HCV-RNA in saliva and its correlation with oral pathology was undertaken. Saliva and blood samples were collected from 50 anti-HCV positive patients and from 25 patients with non-HCV chronic liver disease. HCV-RNA was detected in all of the saliva samples from the HCV positive group. None of the saliva or serum samples from the non-HCV group were positive for HCV-RNA. The patients were examined for dental and oral health (dentate, partially dentate, edentulous, evidence of gum disease, or mucosal lesions); however, no correlation was found between HCV-RNA in saliva, oral health, and viral load. These results suggest that HCV-RNA presence in saliva is independent of the viral load and the oral pathology of HCV positive individuals. J. Med. Virol. 77:216–220, 2005. © 2005 Wiley-Liss, Inc. |
Keywords: | Hepatitis C Saliva Oral pathology |
metadata.dc.rights: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/13756 |
Issue Date: | 2005 |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
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Herbert.pdf | 88,75 kB | Adobe PDF | View/Open |
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