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metadata.dc.type: | Artigo de Periódico |
Title: | Polymerase chain reaction (PCR) is highly sensitive for diagnosis of mucosal leishmaniasis |
Other Titles: | Acta Tropica |
Authors: | Oliveira, Jene Greyce S. Novais, Fernanda O. Oliveira, Camila Indiani de Cruz Junior, Antonio C. da Campos, Léon Fábio Rocha, Any V. da Boaventura, Viviane Sampaio Noronha, Almério Libório Lopes de Costa, Jackson M. L. Barral, Aldina Maria Prado |
metadata.dc.creator: | Oliveira, Jene Greyce S. Novais, Fernanda O. Oliveira, Camila Indiani de Cruz Junior, Antonio C. da Campos, Léon Fábio Rocha, Any V. da Boaventura, Viviane Sampaio Noronha, Almério Libório Lopes de Costa, Jackson M. L. Barral, Aldina Maria Prado |
Abstract: | We evaluated the use of polymerase chain reaction (PCR) for diagnosis of mucosal leishmaniasis (ML) in an endemic area in Acre, Brazil, where Leishmania braziliensis is present. Leishmania DNA was detected 34 of 35 cases, yielding a positivity rate of 97.1%, which was higher than the positivity rates for all of the other diagnostic methods studied, namely Montenegro skin test (MST), anti-Leishmania serological testing and microscopic examination of lesion biopsy specimens. These findings have led us to propose guidelines for the diagnosis of ML that use PCR as the principal method of parasitological confirmation of cases. |
Keywords: | Polymerase chain reaction Leishmania braziliensis Mucosal leishmaniasis |
Publisher: | Elsevier |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/6556 |
Issue Date: | Apr-2005 |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
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