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https://repositorio.ufba.br/handle/ri/5896
metadata.dc.type: | Artigo de Periódico |
Title: | Botulinum toxin type A for the treatment of the upper limb spasticity after stroke: a meta-analysis |
Other Titles: | Arq Neuropsiquiatr |
Authors: | Cardoso, Eduardo Rodrigues, Bernardo Lucena, Rita de Cássia Saldanha de Oliveira, Irismar Reis de Pedreira, Glícia Melo, Ailton de Souza |
metadata.dc.creator: | Cardoso, Eduardo Rodrigues, Bernardo Lucena, Rita de Cássia Saldanha de Oliveira, Irismar Reis de Pedreira, Glícia Melo, Ailton de Souza |
Abstract: | Muscle over-activity is one of the cardinal features of spasticity and it is a common disability of stroke patients. In this group, spasticity is responsible for several limitations that interfere in their daily activities and quality of life. To treat spasticity, neurologists usually prescribe drugs as baclofen, tizanidine or benzodiazepines or even use definitive treatment as phenol or surgery. Authors suggest the use of botulinum toxin type A (BTX-A) for spasticity in the upper limbs after stroke, but there are few papers with adequate methodology supporting this idea. In this article we summarize the data of previous double-blind, randomized clinical trials to asses, with a meta-analysis, if BTX-A is an adequate treatment for spasticity due to stroke. The results show a statistical superiority of BTX-A ov%r placebo on reducing muscle tone by the Modified Ashworth Scale (WMD= 0.95 [0.74 to 1.17]) in patients with post-stroke upper limb spasticity. |
Keywords: | Stroke Spasticity Botulinum toxin Rehabilitation |
Publisher: | Associação Arquivos de Neuro-Psiquiatria Dr. Oswaldo Lange |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/5896 |
Issue Date: | 2005 |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Files in This Item:
File | Description | Size | Format | |
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Cardoso, Eduardo.pdf | 269,28 kB | Adobe PDF | View/Open |
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