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Campo DC | Valor | Idioma |
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dc.contributor.author | Frota, Cristiane C. | - |
dc.contributor.author | Freitas, Max V. C. | - |
dc.contributor.author | Foss, Norma T. | - |
dc.contributor.author | Lima, Luana Nepomuceno Costa | - |
dc.contributor.author | Rodrigues, Laura C. | - |
dc.contributor.author | Barreto, Mauricio Lima | - |
dc.contributor.author | Kerr, Ligia Regina Franco Sansigolo | - |
dc.creator | Frota, Cristiane C. | - |
dc.creator | Freitas, Max V. C. | - |
dc.creator | Foss, Norma T. | - |
dc.creator | Lima, Luana Nepomuceno Costa | - |
dc.creator | Rodrigues, Laura C. | - |
dc.creator | Barreto, Mauricio Lima | - |
dc.creator | Kerr, Ligia Regina Franco Sansigolo | - |
dc.date.accessioned | 2012-05-04T10:49:07Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 0035-9203 | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/5768 | - |
dc.description | Acesso restrito:Texto completo. p.490-495 | pt_BR |
dc.description.abstract | The seroprevalence rates of IgM anti-phenolic glycolipid-I (PGL-I) antibodies in four study groups with differing exposure to Mycobacterium leprae in Ceará, Brazil were investigated between March 2005 and August 2006. The first three groups in a high prevalence area included 144 cases of leprosy, their 380 contacts and 317 participants with no known leprosy contact. The fourth group in a low prevalence area consisted of 87 participants with no known leprosy contact living in an area in which no cases of leprosy had been reported in the previous 6 months. Seropositivity and levels of IgM antibodies to PGL-I were investigated using ELISA. The seropositivity levels of anti-PGL-I among the different clinical forms of leprosy cases were 61% for lepromatous, 25% for tuberculoid and 27% indeterminate. The levels of anti-PGL-I antibodies in the endemic area differentiated leprosy cases from noncases. However, the seropositivity was similar among contact cases (15.8%) and no known leprosy contact cases from high (15.1%) and low (13.8%) prevalence areas. The seropositivity of both contacts and no known contacts was much higher than previously reported among no known contacts in other endemic areas. The study indicates that anti-PGL-I antibodies are not useful as immunological markers of household leprosy contacts and no known leprosy contacts in endemic areas. | pt_BR |
dc.language.iso | en | pt_BR |
dc.source | DOI: 10.1016/j.trstmh.2010.03.006 | pt_BR |
dc.subject | Leprosy | pt_BR |
dc.subject | Mycobacterium leprae | pt_BR |
dc.subject | Seroprevalence | pt_BR |
dc.subject | Immunologic marker | pt_BR |
dc.subject | Phenolic glycolipid-I | pt_BR |
dc.subject | Brazil | pt_BR |
dc.title | Seropositivity to anti-phenolic glycolipid-I in leprosy cases, contacts and no known contacts of leprosy in an endemic and a non-endemic area in northeast Brazil | pt_BR |
dc.title.alternative | Transactions of the Royal Society of Tropical Medicine and Hygiene | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v. 104, n. 7 | pt_BR |
dc.embargo.liftdate | 10000-01-01 | - |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina) |
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