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https://repositorio.ufba.br/handle/ri/5488
metadata.dc.type: | Artigo de Periódico |
Title: | Toxocara canis infection is associated with eosinophilia and total IgE in blood donors from a large Brazilian centre |
Other Titles: | Tropical Medicine & International Health |
Authors: | Dattoli, Vitor Camilo Cavalcante Freire, Songeli Menezes Mendonça, Lívia Ribeiro Santos, P. C. Nascimento, Roberto José Meyer Neves, Neuza Maria Alcântara |
metadata.dc.creator: | Dattoli, Vitor Camilo Cavalcante Freire, Songeli Menezes Mendonça, Lívia Ribeiro Santos, P. C. Nascimento, Roberto José Meyer Neves, Neuza Maria Alcântara |
Abstract: | To investigate the association between Toxocara canis infection and total IgE levels and eosinophilia in blood donors from a large Brazilian city.methods Two hundred and sixty-eight blood donors from a government blood bank were tested. No helminth infection was diagnosed by parasitological stool examination. Total IgE levels and T. canis infection status were determined by ELISA. Eosinophil levels were determined using an automatic blood cell counter. results Toxocara canis IgG antibodies were found in 124 (46.3%); 102 (38.0%) had eosinophilia ‡4% and 29 (10.8%) had eosinophilia ‡10%, respectively; 140 (52.2%) individuals had total IgE antibodies above the cut-off levels. Both total IgE and eosinophil levels ‡10% were positively associated with the infection. conclusion This study revealed a high prevalence of T. canis infection in blood donors, highlighting the need for screening for this infection. It also demonstrated that this population otherwise healthy has higher levels of blood eosinophils and total IgE and that both parameters are associated with T. canis infection. |
Keywords: | Toxocara canis Blood donors Eosinophilia Total IgE Prevalence |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/5488 |
Issue Date: | Apr-2011 |
Appears in Collections: | Artigo Publicado em Periódico Estrangeiro (ISC) |
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