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metadata.dc.type: Artigo de Periódico
Título : Model of induction of thyroid dysfunctions in adult female mice
Otros títulos : Arq. Bras. Med. Vet. Zootec
Autor : Ferreira, E.
Lima, Alessandra Estrela da Silva
Serakides, R.
Gomes, A. S.
Cassali, Geovanni Dantas
metadata.dc.creator: Ferreira, E.
Lima, Alessandra Estrela da Silva
Serakides, R.
Gomes, A. S.
Cassali, Geovanni Dantas
Resumen : It is described the elaboration of a protocol to induce hyperthyroidism and hypothyroidism in mice by administrating thyroxin and propylthiouracil, respectively, in the drinking water. The drugs were administered to adult female mice of the Swiss strain for 30 days in order to obtain a systemic status of thyroid dysfunction. The induction of hyperthyroidism and hypothyroidism in the animals was confirmed by the histomorphological analysis of the thyroid in the end of the experiment, when the state of gland dysfunction in the animals submitted to the treatment was observed.
Palabras clave : mouse
thyroid
protocol
induction
thyroxin
propylthiouracil
URI : http://www.repositorio.ufba.br/ri/handle/ri/5349
Fecha de publicación : 2007
Aparece en las colecciones: Artigo Publicado em Periódico (EMV)

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