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https://repositorio.ufba.br/handle/ri/5254
metadata.dc.type: | Artigo de Periódico |
Title: | First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil |
Other Titles: | Cad. Saúde Pública |
Authors: | Silva, Aída Cristina do Nascimento Ferrazoli, Lucilaine Simonsen, Vera Reis, Joice Neves Pereira, Susan Martins Carmo, Theomira Mauadie Azevedo Mota, Eduardo Luiz Andrade Reis, Mitermayer Galvão |
metadata.dc.creator: | Silva, Aída Cristina do Nascimento Ferrazoli, Lucilaine Simonsen, Vera Reis, Joice Neves Pereira, Susan Martins Carmo, Theomira Mauadie Azevedo Mota, Eduardo Luiz Andrade Reis, Mitermayer Galvão |
Abstract: | This study constitutes a first attempt to describe the genetic population structure of Mycobacterium tuberculosis circulating in Salvador, Bahia State, Brazil. A total of 56 confirmed cases of pulmonary tuberculosis, identified between March and June 2008, were analyzed using restriction fragment length polymorphism (IS6110-RFLP). The study population was characterized by a predominance of males (71.43%) over 30 years of age (68.75%). Forty-one isolates were found to belong to a single pattern (73.2%), while 15 (26.7%) were found in group patterns, forming six clusters. The higher level of diversity observed is much more suggestive of endogenous reactivation than recent transmission. |
Keywords: | Tuberculosis Molecular Epidemiology Genetic Variation Mycobacterium tuberculosis |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/5254 |
Issue Date: | 2011 |
Appears in Collections: | Artigo Publicado em Periódico Nacional (ISC) |
Files in This Item:
File | Description | Size | Format | |
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EMota 2011. Repositorio.pdf | 197,69 kB | Adobe PDF | View/Open |
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