Investigação da contaminação por chumbo em medicamentos utilizados na terapêutica da anemia ferropriva

Abstract

In this work is presented the development of a analytical strategy for investigate the lead content in medicines used in the anemia ferropriva treatment commercialized in Brazil. For investigation, was developed an analytical strategy utilizing electrothermal atomic absorption spectrometry. In this study, performed in Research group of Chemistry and Chemometrics in Federal University of Bahia – UFBA, fourteen commercial samples of medicines largement utilized for anemia treatment were selected, being samples of liquid medicines and solid medicines samples (in tablets). The method was validated or according with International United of Pure and Applied Chemistry and the International Harmonisation Conference of Technical Requirements for medicines samples. The obtained values were calculated with National Agencia of Sanitary Vigilance. As not exist a regulamentation in Brazilian Pharmacopoeia for the lead values, for the analysis type, considering the risk of ingested inorganic impurities during large time, as is the case of anemia.