Avaliação do perfil clínico e mensuração da rigidez hepática através da elastografia por ondas de cisalhamento em pacientes com cirrose hepática

Abstract

Introduction: Liver cirrhosis is highly prevalent in the world and has significant morbidity and mortality. Non invasive methods for assessement of hepatic fibrosis have been proposed, aiming avoid exposure to invasive procedures such as liver biopsy, being elastography one of the alternatives. Objective: Evaluating the association the clinical profile of liver disease analyzed by the Child-Pugh and Meld scores with the measurement of hepatic rigidity obtained through two-dimensional shear wave elastography (Real Time Shear Wave 2D Elastography). Methods: Cross-sectional, descriptive study, from January 2015 to September 2016. Inclusion criteria were: age ≥ 18 years, previous diagnosis of cirrhosis and signing consent term individuals. Were excluded patients with suggestive or diagnosis of hepatic nodules of hepatocellular carcinoma, HIV infection and hepatic encephalopathy at the time of selection. Results: Twelve patients were included in the study, of which 75% were males, the median age was 53.5 years, and the most frequent etiology of liver disease was chronic alcoholic liver disease corresponding to 50% of the sample. The mean value of liver stiffness measured by Shear Wave elastography was 34.4 kPa, with a mean of 26.54 kPa. The 12 patients were Child B. Conclusions: The degree of liver stiffness obtained by the elastography was consistent with the advanced fibrosis stage (F3 / F4) on the METAVIR scale.