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Use este identificador para citar ou linkar para este item: https://repositorio.ufba.br/handle/ri/17663
Tipo: Artigo de Periódico
Título: Prevalence of celiac disease in children with epilepsy
Título(s) alternativo(s): Arquivos de Gastroenterologia
Autor(es): Vieira, Camilo
Jatobá, Izabele
Matos, Marília
Santos, Daniel Diniz
Silva, Luciana R.
Autor(es): Vieira, Camilo
Jatobá, Izabele
Matos, Marília
Santos, Daniel Diniz
Silva, Luciana R.
Abstract: Context Neurological symptoms have been well-documented in patients with celiac disease, nevertheless, the presumption of a greater prevalence of epilepsy in celiac patients remains controversial. Objectives To determine the frequency of celiac disease in children and adolescents with idiopathic or cryptogenic epilepsy. Methods A cross-sectional study. One hundred pediatric patients with non-symptomatic epilepsy were followed-up at two public pediatric neurology clinics in Salvador, Bahia, Brazil. Screening for celiac disease was performed by serial measurements of IgA anti-transglutaminase and IgA anti-endomysium antibodies, followed by bowel biopsy in positive cases. HLA DQ02 and DQ08 were investigated in seropositive individuals, assessing the type of seizures, the number of antiepileptic drugs used and the presence gastrointestinal symptoms. Results Three (3.0%) patients tested anti-tTG-positive, two with normal duodenal mucosa (Marsh 0) and one with intraepithelial infiltrate (Marsh I). No villous atrophy of the duodenal mucosa (Marsh III) celiac disease was found. Two patients tested positive for HLA DQ02; none were DQ08 positive. Conclusion The present study failed to prove the association between celiac disease and epilepsy.
Palavras-chave: Celiac disease
Epilepsy
Disabled children
País: Brasil
Tipo de Acesso: Acesso Aberto
URI: http://repositorio.ufba.br/ri/handle/ri/17663
Data do documento: 2013
Aparece nas coleções:Artigo Publicado em Periódico (Faculdade de Medicina)

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