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dc.contributor.authorVieira, Camilo-
dc.contributor.authorJatobá, Izabele-
dc.contributor.authorMatos, Marília-
dc.contributor.authorSantos, Daniel Diniz-
dc.contributor.authorSilva, Luciana R.-
dc.creatorVieira, Camilo-
dc.creatorJatobá, Izabele-
dc.creatorMatos, Marília-
dc.creatorSantos, Daniel Diniz-
dc.creatorSilva, Luciana R.-
dc.description.abstractContext Neurological symptoms have been well-documented in patients with celiac disease, nevertheless, the presumption of a greater prevalence of epilepsy in celiac patients remains controversial. Objectives To determine the frequency of celiac disease in children and adolescents with idiopathic or cryptogenic epilepsy. Methods A cross-sectional study. One hundred pediatric patients with non-symptomatic epilepsy were followed-up at two public pediatric neurology clinics in Salvador, Bahia, Brazil. Screening for celiac disease was performed by serial measurements of IgA anti-transglutaminase and IgA anti-endomysium antibodies, followed by bowel biopsy in positive cases. HLA DQ02 and DQ08 were investigated in seropositive individuals, assessing the type of seizures, the number of antiepileptic drugs used and the presence gastrointestinal symptoms. Results Three (3.0%) patients tested anti-tTG-positive, two with normal duodenal mucosa (Marsh 0) and one with intraepithelial infiltrate (Marsh I). No villous atrophy of the duodenal mucosa (Marsh III) celiac disease was found. Two patients tested positive for HLA DQ02; none were DQ08 positive. Conclusion The present study failed to prove the association between celiac disease and epilepsy.pt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectCeliac diseasept_BR
dc.subjectDisabled childrenpt_BR
dc.titlePrevalence of celiac disease in children with epilepsypt_BR
dc.title.alternativeArquivos de Gastroenterologiapt_BR
dc.typeArtigo de Periódicopt_BR
dc.identifier.numberv. 50, n. 4pt_BR
Appears in Collections:Artigo Publicado em Periódico (Faculdade de Medicina)

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