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https://repositorio.ufba.br/handle/ri/16680| metadata.dc.type: | Artigo de Periódico |
| Title: | Th1/Th2 Cytokine Profile in Patients Coinfected with HIV and Leishmania in Brazil |
| Other Titles: | Clinical and Vaccine Immunology |
| Authors: | Rodrigues, Maria Zilma Andrade Grassi, Maria Fernanda Rios Mehta, Sanjay R. Zhang, Xing-Quan Gois, Luana Leandro Schooley, Robert T. Badaró, Roberto José da Silva |
| metadata.dc.creator: | Rodrigues, Maria Zilma Andrade Grassi, Maria Fernanda Rios Mehta, Sanjay R. Zhang, Xing-Quan Gois, Luana Leandro Schooley, Robert T. Badaró, Roberto José da Silva |
| Abstract: | To evaluate the effects of HIV on immune responses in cutaneous leishmaniasis (CL), we quantified cytokine levels from plasma and stimulated peripheral blood mononuclear cells (PBMCs) from individuals infected with HIV and/or CL. Gamma interferon (IFN-γ) and interleukin 13 (IL-13) levels and the ratio of IFN-γ to IL-10 produced in response to stimulation with soluble Leishmania antigens were significantly lower in HIV-Leishmania-coinfected patients than in CL-monoinfected patients. |
| Keywords: | Th1 Cells Th2 Cells Leishmaniasis cutaneous HIV Infections |
| metadata.dc.rights: | Acesso Aberto |
| URI: | http://repositorio.ufba.br/ri/handle/ri/16680 |
| Issue Date: | 2011 |
| Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Roberto Badaro.pdf | 440,89 kB | Adobe PDF | View/Open |
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