https://repositorio.ufba.br/handle/ri/13439
metadata.dc.type: | Artigo de Periódico |
Title: | Risk factors for infection by extended-spectrum beta-lactamase producing Klebsiella pneumoniae in a tertiary hospital in Salvador, Brazil |
Other Titles: | Brazilian Journal of Infectious Diseases |
Authors: | Brites, Carlos Silva, Nanci Oliveira, Márcio Bandeira, Antonio Carlos de Albuquerque |
metadata.dc.creator: | Brites, Carlos Silva, Nanci Oliveira, Márcio Bandeira, Antonio Carlos de Albuquerque |
Abstract: | Nosocomial infection caused by extended-spectrum beta-lactamase producing Klebsiella pneumoniae (ESBL-Kp) have been frequently reported worldwide. We have no information on such problems in Bahia, Brazil. OBJECTIVES: Evaluate the risk factors for nosocomial infections caused by ESBL-Kp, in a tertiary hospital, in Bahia, Brazil. MATERIAL AND METHODS: We evaluated all reported cases of nosocomial infections caused by ESBL-Kp in a private, tertiary hospital, in Salvador, Brazil, from 2000 through 2004. We compared patients with a diagnosis of ESBL-Kp (cases) and patients infected by non-ESBL producing K. pneumoniae (controls). Mean age, underlying disease, and frequency of invasive procedures were compared between the two groups. History of previous use of antibiotics was also analyzed. RESULTS: Based on multivariate analysis, previous use of antibiotics, diagnosis of malignant diseases, and diabetes mellitus were independent risk factors for acquisition of ESBL-Kp infection. No correlation was found for age, use of corticosteroids, diagnosis of chronic renal failure or AIDS, and infection by ESBL-Kp. CONCLUSION: Our findings suggest that the use of antibiotics or underlying disease that increases the chance of antibiotic are the main risk factors for ESBL-Kp infections. Programs focusing on rational use of antibiotics are mandatory for prevention and control of such infections. |
Keywords: | Nosocomial infections ESBL Klebsiella pneumoniae Bacterial resistance |
metadata.dc.rights: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/13439 |
Issue Date: | 2006 |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
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a07v10n3.pdf | 73,92 kB | Adobe PDF | View/Open |
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