Resumo:
Introduction: Down Syndrome (DS) is a genetic condition resulting from the
presence of a third chromosome in pair 21. Currently, the life expectancy of
individuals with DS has increased significantly, ranging from 40 to 60 years. From this
perspective, premature aging is present in this population with significant
characteristics and associated declines. Objective: To analyze interventions
associated with cognitive and physical functions performed with adults with DS, and
their possible relationships with premature aging. Methodology: This study is an
integrative review conducted between April and May 2025 with searches in the
following databases: PubMed, Bireme, SciELO and Portal Periódicos Capes.
Results: A total of 186 articles were identified, and after applying the inclusion
criteria, 9 articles were selected to compose this review. These studies included
between 12 and 83 adults and elderly people with DS, aged between 24 and 62
years, who underwent cognitive and/or physical interventions lasting between 5
hours and 12 weeks. The publication years range from 2004 to 2024, with the
majority of studies published in 2019. Of these, 5 articles presented the term
"premature aging" during the breakdown of their research. Conclusion: The potential
of interventions in minimizing the impacts of premature aging and maintaining
functionality in this population is evident. Finally, the emphasis on limitations in
activities of daily living(ADL) and restricted participation, mentioned in the articles
associated with premature aging, makes the need for Occupational Therapy
intervention clear.
