Acute myeloid leukemia (AML) is caused by the clonal proliferation of precursor cells of the myeloid lineage. The diagnosis of AML is made by identifying clinical and laboratory signs, including the percentage of leukemic ...

Introduction: Allergies to house dust mites, such as Blomia tropicalis and Dermatophagoides pteronyssinus, represent a major public health problem. Molecular and immunological characterization of allergens from these ...

Traumatic Brain Injury (TBI) is a complex and multifactorial pathology, being a major cause of death and disability for humans. Immediately after TBI, astrocytes and microglia react with complex morphological and functional ...

COVID-19 is a disease that began in the city of Wuhan, China, and quickly spread across the world, leading the World Health Organization to declare a pandemic in March 2020. Due to the high number of deaths caused by ...

Introduction: Dust mites are considered one of the main sources of aeroallergens and are associated with the development of allergic diseases. In Brazil, the most prevalent mites belong to the genera Dermatophagoides spp ...

COVID-19 is an acute respiratory disease caused by the coronavirus SARS-CoV-2. Its progression has been associated with hypoxia, unregulated systemic inflammation and coagulopathies, but the risk factors for its progression ...

Introduction: Sepsis is a global public health problem and represents the leading cause of morbidity and mortality worldwide in non-cardiac intensive care units. The incidence and mortality of the sepsis are still high, ...

Introduction: COVID-19 is characterized by hyperactivation of the immune system and uncontrolled release of cytokines. Recent studies indicate that impaired signaling of IFNA1 and its receptors, IL17A, HERVs and IFN-γ may ...

Introduction: Periodontitis involves bone loss of support tissue and consequent loss of dental units, which significantly impacts the quality of life of individuals from all walks of life. The presence of dysbiotic microbial ...

Glaucoma is a very common condition and its diagnosis is often difficult and late. BDNF is a neuropeptide whose trophic function helps protect retinal ganglion cells. Low levels of BDNF have been associated with glaucoma ...