Acute myeloid leukemia (AML) is caused by the clonal proliferation of precursor cells of the myeloid lineage. The diagnosis of AML is made by identifying clinical and laboratory signs, including the percentage of leukemic ...

Introduction: Allergies to house dust mites, such as Blomia tropicalis and Dermatophagoides pteronyssinus, represent a major public health problem. Molecular and immunological characterization of allergens from these ...

Traumatic Brain Injury (TBI) is a complex and multifactorial pathology, being a major cause of death and disability for humans. Immediately after TBI, astrocytes and microglia react with complex morphological and functional ...

The clinical spectrum of COVID-19 is quite variable, and may present as asymptomatic, with mild involvement of the upper respiratory tract and progression to severe pneumonia with respiratory failure, failure and even ...

Osteonecrosis and leg ulcers are tissue injuries associated with microvascular complications commonly found in patients with sickle cell disease (SCD). Since these comorbidities have limited treatment options, the use ...

Multiple Myeloma (MM) is the second most common hematological malignancy, resulting from the proliferation of monoclonal protein-producing plasma cells, predominantly affecting the elderly population. In the last decade, ...

Introduction: Dust mites are considered one of the main sources of aeroallergens and are associated with the development of allergic diseases. In Brazil, the most prevalent mites belong to the genera Dermatophagoides spp ...

Introduction: Multisystem Inflammatory Syndrome in Children (MIS-C) is an inflammatory condition associated with SARS-CoV-2 infection. It is characterized by fever, prominent gastrointestinal symptoms, mucocutaneous ...

Asthma is a highly complex immune-mediated disease, characterized by a reversible and intermittent obstruction of the airways that, despite having a higher prevalence in childhood, has shown a high incidence and mortality ...

Asthma is a chronic inflammatory disease of the airways, non-transmissible, influenced by environmental and genetic factors. Allergic asthma is the most common phenotype of the disease and is associated with an exacerbation ...