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Navegação Artigo Publicado em Periódico (FAR) por título

Navegação Artigo Publicado em Periódico (FAR) por título

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  • 2-Quinolone alkaloids from the rare species of Rutaceae Andreadoxaflava Kallunki 
    Hohlemwerger, Sandra Virgínia Alves; Carvalho, André Maurício de; Velozo, Eudes da Silva; Tavares, Waldir; Vieira, Paulo Cezar (2004)
  • 2D chemometric studies of a series of azole derivatives active against fluconazole-resistant Cryptococcus gattii 
    Freitas, Humberto F.; Barros, Tânia Fraga; Castilho, Marcelo Santos (Brasil, 2013)
    Despite advances in the development of antifungal drugs,there has been an upsurge of cryptococosis infections that poorly respond to fluconazole (first choice drug). Hence,it is paramount to investigate the chemical ...
  • 2D Chemometrics Analyses of Tetrahydroquinoline and Ethylenediamine Derivatives with Antimalarial Activity 
    Freitas, Humberto Fonseca de; Castilho, Marcelo Santos (2012)
    Malaria, one of the most widespread and deadly infectious diseases continues to kill over 1 million people every year. This scenario is getting even worse as P. falciparum develops resistance to existing drugs. Thus, there ...
  • 2D QSAR studies on thyroid hormone receptor ligands 
    Valadares, Napoleão F.; Castilho, Marcelo Santos; Polikarpov, Igor; Garratt, Richard C. (2007)
    2D QSAR studies were carried out for a series of 55 ligands for the Thyroid receptors, TRα and TRβ. Significant cross-validated correlation coefficients (q2 = 0.781 (TRα) and 0.693 (TRβ)) were obtained. The models’ predictive ...
  • 2D Quantitative structure–activity relationship studies on a series of cholesteryl ester transfer protein inhibitors 
    Castilho, Marcelo Santos; Guido, Rafael V. C.; Andricopulo, Adriano D. (2007)
    Coronary heart disease (CHD) is one of the major causes of human death. The most successful therapeutic approach available is based on the reduction of low density-lipoprotein cholesterol (LDL-C). However, it is believed ...
  • Acetylcholinesterase activity of alkaloids from the leaves of Waltheria brachypetala 
    Lima, Murilo M. C.; López, Jorge A.; David, Jorge Mauricio; Silva, Eliezer P.; Giulietti, Ana M.; Queiroz, Luciano Paganucci de; David, Juceni Pereira de Lima (2009)
    Chemical investigation of the leaves of Waltheria brachypetala Turks (Sterculiaceae) resulted in the isolation of quinolinone alkaloids, waltherione-A, waltherione-B (N-methylwaltherione-A), 8-methoxyflindersine, and the ...
  • Adverse drug reactions at a university hospital in Brazil 
    Toledo, Leonardo Augusto Kister de; Noblat, Lúcia de Araújo Costa Beisl; Noblat, Antonio Carlos Beisl; Oliveira, M. G.; Santos, P. M. (2010)
    The aim of this study is to characterize the patients and the ADR notified to a Pharmacovigilance Center at a university hospital in Brazil. The ADR rate in hospitalized patients is 10% to 20% and the frequency of ...
  • Alcaloides das cascas das raízes de Zanthoxylum spp 
    Hohlemwerge, Sandra Virgínia Alves; Sales, Edijane Matos; Costa, Rafael dos Santos; Velozo, Eudes da Silva; Guedes, Maria Lenise da Silva (Brasil, 2012)
    In 1959, Gottlieb and Antonaccio published a study reporting the occurrence of lignan sesamin and triterpene lupeol in Zanthoxylum tingoassuiba. In this work we describe the phytochemical study of the root bark of the Z. ...
  • Alcalóides e outros metabólitos do caule e frutos de Zanthoxylum tingoassuiba A. St. Hil 
    Silva, Cinara Vasconcelos da; Detoni, Cássia Britto; Velozo, Eudes da Silva; Guedes, Maria Lenise da Silva (2008)
    Phytochemical investigation of this species, popularly known as tinguaciba and used in traditional medicine to various diseases, resulted in the isolation of 15 substances: 2 alkaloids - norchelerythrine and arnottianamide; ...
  • An experimental protocol for the establishment of dogs with long-term cellular immune reactions to Leishmania antigens 
    Teixeira, Márcia Cristina Aquino; Oliveira, Geraldo Gileno de Sá; Santos, Patrícia Oliveira Meira; Bahiense, Thiago Campanharo; Silva, Virginia Maria Goes da; Rodrigues, Márcio Silva; Larangeira, Daniela Farias; Santos, Washington Luis Conrado dos; Carvalho, Lain Carlos Pontes de (2011-03)
    Domestic dogs are considered to be the main reservoirs of zoonotic visceral leishmaniasis. In this work, we evaluated a protocol to induce Leishmania infantum/Leishmania chagasi-specific cellular and humoral immune responses ...
  • An improved anti-C3/IgG ELISA for quantification of soluble immune complexes 
    Soares, Neci Matos; Santiago, Mittermayer Barreto; Carvalho, Lain Carlos Pontes de (2001)
    A semi-quantitative ELISA for complement-fixing, IgG-containing immune complexes (IC) is described. The assay is based on the insolubilization of IC by polyethyleneglycol, their capture by solid-phase anti-C3 antibodies, ...
  • Analgésicos inibidores específicos da ciclooxigenase-2: avanços terapêuticos 
    Carvalho, Wilson Andrade de; Carvalho, Rosemary Duarte Sales; Rios-Santos, Fabrício (2004)
    JUSTIFICATIVA E OBJETIVOS: Os antiinflamatórios não-esteroidais (AINE) estão entre as drogas mais prescritas e usadas no mundo, incluindo a utilização em Anestesiologia. O propósito desta revisão é discutir alguns aspectos ...
  • Analysis of the use of imipenem at a University Hospital following the restructuring of an antimicrobial audit system 
    Souza, N. P.; Noblat, Antonio Carlos Beisl; Noblat, Lúcia de Araújo Costa Beisl (2008)
    This study analyzed the use pattern of imipenem following the restructuring of the antimicrobial audit system at a University Hospital. It was an observational study before and after the restructuring of the antimicrobial ...
  • Análise de risco aplicada aos alimentos no Brasil: perspectivas e desafios 
    Figueiredo, Ana Virgínia de Almeida; Miranda, Maria da Pureza Spínola (Associação Brasileira de Pós-Graduação em Saúde Coletiva, 2011-04)
    Trata-se de um estudo de caso no qual se discutiram as ideias do Comitê do Codex Alimentarius do Brasil (CCAB), coordenado pelo Instituto Nacional de Metrologia, Normalização e Qualidade Industrial (Inmetro) sobre a norma ...
  • Anti-allergic effect of bee pollen phenolic extract and myricetin in ovalbumin-sensitized mice 
    Medeiros, K. C. P.; Figueiredo, C. A. V.; Figueredo, T. B.; Freire, K. R. L.; Santos, F. A. R.; Alcântara-Neves, Neuza Maria; Silva, T. M. S.; Piuvezam, M. R. (2008)
    Ethnopharmacological relevance: The bee pollen is used in folk medicine to alleviate allergic reactions. The bee pollen phenolic extract (BPPE) consists in phenolic compounds (flavonoids) from plants picked by Apis mellifera ...
  • Anti-dsDNA antibodies in Brazilian patients of mainly African descent with systemic lupus erythematosus: lack of association with lupus nephritis 
    Atta, Ajax Mercês; Pereira, Mariana de Menezes; Santiago, Mittermayer Barreto; Atta, Maria Luiza Brito de Sousa (2009)
    Renal disease is associated with morbidity and mortality in systemic lupus erythematosus (SLE) and antidsDNA antibodies with SLE immunopathogenesis. We investigated the dsDNA antibody profile of 84 Brazilian SLE patients, ...
  • Anti-inflammatory effects of carvacrol: evidence for a key role of interleukin-10 
    Lima, Milena da Silva; Quintans Júnior, Lucindo José; Santana, Wagno Alcântara de; Kaneto, Carla Martins; Soares, Milena Botelho Pereira; Villarreal, Cristiane Flora (European Journal of Pharmacology, 2013)
    Carvacrol, a phenolic monoterpene, has been reported to possess anti-inflammatory properties. However, the mechanisms involved in its pharmacological properties are currently not well understood. In the present study, the ...
  • Anti-inflammatory properties of rose oxide 
    Villarreal, Cristiane Flora; Melo, Flavielle Martins de; Nonato, Fabiana Regina; Santana, Daniele Gomes; Santos, Gisele Graça Leite dos; Brustolim, Daniele; Camargo, Enilton Aparecido; Sousa, Damião P. de (2012)
    Rose-oxide is a fragrance found in roses and rose oil. There are no reports about the pharmacological activity of this molecule. The present study was undertaken to evaluate whether rose-oxide (RO) has anti-inflammatory ...
  • Anti-leishmanial ige antibodies: a marker of active disease in visceral leishmaniasis 
    Atta, Ajax Mercês; D'Oliveira Junior, Argemiro; Correa, Jefferson; Atta, Maria Luiza Brito de Sousa; Almeida, Roque Pacheco de; Carvalho Filho, Edgar Marcelino de (The American Society of Tropical Medicine and Hygiene, 1998)
    Abstract. Visceral leishmaniasis (VL) is characterized by a depression of the T helper cell type 1 immune response. Although mRNA expression for interleukin-4 (IL-4) is observed, evidence of the role of this cytokine in ...
  • Antiinflammatory and antinociceptive activities of Blechnum occidentale L. extract 
    Nonato, Fabiana Regina; Barros, Taís Adelita de Almeida; Lucchese, Angélica Maria; Oliveira, Carlos Eduardo Cordeiro; Santos, Ricardo Ribeiro dos; Soares, Milena Botelho Pereira; Villarreal, Cristiane Flora (Elsevier, 2009)
    Blechnum occidentale L. is a terrestrial fern that ranges from the United States to South America, and is employed in Brazilian folk medicine. In the present study we investigated the antinociceptive and antiinflammatory ...