Huang, Lili; Gao, Li; Figueiredo, Camila; Rafaels, Nicholas M.; Vergara, Candelaria I.; Ruczinski, Ingo; Beaty, Terri H.; Barnes, Kathleen C.; Mathias, Rasika A.
(Journal of Allergy and Clinical Immunology, 2013)
Rationale
ST2 (IL1RL1), is an IL1 family receptor that mediates important effectors of Th2 functions. Its soluble form (sST2) neutralizes its ligand, IL-33, by acting as a decoy receptor. Serum sST2 has been used as a ...