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Please use this identifier to cite or link to this item: http://repositorio.ufba.br/ri/handle/ri/7738

Title: Carbohydrate metabolism in sickle cell patients using a subdermal implant containing nomegestrol acetate (Uniplant)
Other Titles: Contraception
Authors: Barbosa, Ione Cristina
Ladipo, Oladapo A.
Lourdes, Maria de
Nascimento, P.
Athayde, Célia Maria Soares
Hirsch, Cristina
Lopes, Renata
Matias, Bruno
Coutinho, Elsimar Metzker
Keywords: Uniplant;Contraceptives;Sickle cell;Glucose tolerance test
Issue Date: 2001
Abstract: Uniplant, a second-generation contraceptive implant, has been demonstrated to promote a significant improvement in the overall well-being of women with sickle cell anemia. It has been suggested that the discrete increase in blood glucose levels observed in Uniplant users could be a contributory factor for clinical improvement. Ten healthy sickle cell patients were enrolled in the study. An oral glucose tolerance test was performed prior to implant insertion and at 1, 6, and 12 months of therapy. Blood glucose and insulin were measured before and at 30, 60, 120, and 180 min after a 75-g glucose load. The glucose and insulin areas under the curves were calculated. Fasting glycosylated hemoglobin was also measured. No significant changes were observed in glycosylated hemoglobin, glucose or insulin. We conclude that Uniplant is a safe contraceptive for sickle cell patients.
Description: Texto completo: acesso restrito. p. 263–265
URI: http://www.repositorio.ufba.br/ri/handle/ri/7738
ISSN: 0010-7824
Appears in Collections:Artigos Publicados em Periódicos (Medicina)

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