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Please use this identifier to cite or link to this item: http://repositorio.ufba.br/ri/handle/ri/7023

Title: Prevalence of hepatitis C and B virus infection in patients with idiopathic dilated cardiomyopathy in Brazil: a pilot study
Other Titles: Brazilian Journal of Infectious Diseases
Authors: Reis, Francisco José Farias Borges
Viana, Mateus
Oliveira, Manoela
Sousa, Tiago Almeida de
Paraná, Raymundo
Keywords: Idiopathic dilated cardiomyopathy;Hepatitis C virus;Myocarditis;Heart failure
Issue Date: Jun-2007
Publisher: The Brazilian Journal of Infectious Diseases and Contexto Publishing
Abstract: The idiopathic dilated cardiomyopathy (IDMC) is a disease of the cardiac muscle characterized by systolic dilation and/or dysfunction of one or both ventricles, symptoms of congestive heart failure and risk of early death. Several studies in animal models and in humans have supported the hypothesis of the viral infection as initial event in the immunopathogenesis of the ventricular dilation. The objective of this study was to correlate the presence of hepatitis C virus chronic infection and idiopathic dilated cardiomyopathy, comparing samples of cases with IDCM with paired controls with Chagas-type specific dilated cardiomyopathy and ischemic-type specific dilated cardiomyopathy. Only 2.9% (1/34) of IDCM patients were HCV carriers, which strongly argue against this hypothesis. Therefore, based on our results, there is no justification for investigating HCV in patients with idiopathic dilated cardiomyopathy diagnosis.
Description: p.318-321
URI: http://www.repositorio.ufba.br/ri/handle/ri/7023
ISSN: 1413-8670
Appears in Collections:Artigos Publicados em Periódicos (Faculdade de Medicina)

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