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Please use this identifier to cite or link to this item: http://repositorio.ufba.br/ri/handle/ri/6497

Title: Prevalence of hepatitis C virus infection in north-eastern Brazil: a population-based study
Other Titles: Transactions of the Royal Society of Tropical Medicine and Hygiene
Authors: Zarife, Maria Alice Sant'anna
Silva, Luciano K.
Silva, Maria Betânia S.
Lopes, Gisele Barreto
Barreto, Mauricio Lima
Teixeira, Maria da Glória Lima Cruz
Dourado, Maria Inês Costa
Reis, Mitermayer G.
Keywords: Hepatitis C virus;HCV;Population-based study;Genotype
Issue Date: 2006
Publisher: Transactions of the Royal Society of Tropical Medicine and Hygiene
Abstract: In general, the prevalence and genotype distribution of hepatitis C virus (HCV) are estimated based on the ambulatory clinic or hospital population. In the present work, a population-based study was conducted to estimate the prevalence of HCV infection in Salvador, Brazil. A total of 1308 serum samples were collected from 30 ‘sentinel areas’, and the prevalence of HCV infection was determined by ELISA and confirmed by recombinant immunoblot assay and RT-PCR. The overall prevalence of HCV infection was 1.5% (20/1308). Prevalence was greater among those aged 35 years or older and those with more education. Genotype 3 was the most common (53.3%), followed by genotypes 1 (40%) and 2 (6.7%). These observations are different from those found in a prior survey of hospital and ambulatory patients in Salvador, who were most frequently infected with genotype 1, followed by genotypes 3 and 2, respectively.
Description: RESTRITO
URI: http://www.repositorio.ufba.br/ri/handle/ri/6497
ISSN: 0035-9203
Appears in Collections:Artigos Publicados em Periódicos Estrangeiros (ISC)

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