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|Title: ||Prevalence of hepatitis C virus infection in north-eastern Brazil: a population-based study|
|Other Titles: ||Transactions of the Royal Society of Tropical Medicine and Hygiene|
|Authors: ||Zarife, Maria Alice Sant'anna|
Silva, Luciano K.
Silva, Maria Betânia S.
Lopes, Gisele Barreto
Barreto, Mauricio Lima
Teixeira, Maria da Glória Lima Cruz
Dourado, Maria Inês Costa
Reis, Mitermayer G.
|Keywords: ||Hepatitis C virus;HCV;Population-based study;Genotype|
|Issue Date: ||2006|
|Publisher: ||Transactions of the Royal Society of Tropical Medicine and Hygiene|
|Abstract: ||In general, the prevalence and genotype distribution of hepatitis C virus (HCV) are estimated based on the ambulatory clinic or hospital population. In the present work, a population-based study was conducted to estimate the prevalence of HCV infection in Salvador, Brazil. A total of 1308 serum samples were collected from 30 ‘sentinel areas’, and the prevalence of HCV infection was determined by ELISA and confirmed by recombinant immunoblot assay and RT-PCR. The overall prevalence of HCV infection was 1.5% (20/1308). Prevalence was greater among those aged 35 years or older and those with more education. Genotype 3 was the most common (53.3%), followed by genotypes 1 (40%) and 2 (6.7%). These observations are different from those found in a prior survey of hospital and ambulatory patients in Salvador, who were most frequently infected with genotype 1, followed by genotypes 3 and 2, respectively.|
|Appears in Collections:||Artigos Publicados em Periódicos Estrangeiros (ISC)|
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