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Please use this identifier to cite or link to this item: http://repositorio.ufba.br/ri/handle/ri/5879

Title: Cognitive dysfunction in congestive heart failure: transcranial Doppler evidence of microembolic etiology
Other Titles: Arq Neuropsiquiatr
Authors: Jesus, Pedro Antonio Pereira de
Melo, Rodrigo Morel Vieira de
Reis, Francisco José Farias Borges dos
Viana, Leila Castro
Lacerda, Amanda
Dias, Jesângeli de Sousa
Oliveira Filho, Jamary
Keywords: Transcranial Doppler;Congestive heart failure;Cognitive dysfunction cerebrovascular disorders
Issue Date: Jun-2006
Publisher: Associação Arquivos de Neuro-Psiquiatria Dr. Oswaldo Lange
Abstract: Cognitive symptoms are common in patients with congestive heart failure (CHF) and are usually attributed to low cerebral blood flow. In the present study, we aimed to evaluate global cognitive function (Mini Mental State Exam - MMSE) in relation to both cardiac function (evaluated by echocardiogram) and cere b rovascular hemodynamics (evaluated by transcranial Doppler - TCD) in CHF patients. In 83 patients studied, no correlation was found between echocardiographic parameters and MMSE scores. In contrast, a significant correlation was found between right middle cerebral art e ry (RMCA) mean flow velocity and MMSE score (r=0.231 p=0.039), as well as between RMCA pulsatility index and MMSE score (rs= –0.292 p=0.015). After excluding patients with a previous history of stroke, only RMCA pulsatility index c o rrelated with MMSE score (rs=–0,314 p=0,007). The relationship between high cere b rovascular resistance and worse cognitive scores suggest that microembolism may be Responsible for a significant pro p o rtion of cognitive symptoms in CHF patients.
Description: P.207-210
URI: http://www.repositorio.ufba.br/ri/handle/ri/5879
ISSN: 0004-282X
Appears in Collections:Artigos Publicados em Periódicos (Medicina)

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