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|Title: ||Prevalence of Erectile Dysfunction in HTLV-1–Infected Patients and Its Association With Overactive Bladder|
|Other Titles: ||Urology|
|Authors: ||Oliveira, Paulo|
Castro, Néviton Matos de
Muniz, André Luís Nunes
Brandão, Julio C.
Porto, Maria Aurélia da Fonseca
Carvalho Filho, Edgar Marcelino de
|Issue Date: ||1-May-2010|
|Abstract: ||OBJECTIVES To determine the prevalence of erectile dysfunction (ED) in human T-cell lymphotropic virus
type I (HTLV-I)-infected patients, and its association with overactive bladder (OB).
METHODS In a cross-sectional study, 111 male patients with positive serology for HTLV-I (by enzymelinked
immunosorbent assay and Western blot) were examined between October 2003 and
December 2006. Exclusion criteria were age 18 and 80 years, other neurological diseases,
penile prosthesis, neoplasm, and psychological and mental disease. Patients were evaluated by a
urologist and neurologist. ED was determined by application of the abridged form of 5-item
International Index of Erectile Function (IIEF-5). ED was defined as IIEF-5 21. OB was
determined by International Continence Society criteria. Using the Expanded Disability Status
Scale (EDSS) to determine disautonomy status, a neurologist classified all patients as either
asymptomatic carriers (EDSS 0), “oligosymptomatic myelopathy” (EDSS 0 e 2), or
HTLV-1–associated myelopathy/tropical spastic paraparesis (HAM/TSP); (EDSS 2). Diagnosis
of HAM/TSP was performed according to World Health Organization recommendations.
RESULTS Of the total of 111 patients, 6 were excluded and 105 were analyzed. The mean age was 48
10.7 years. ED was observed in 55.2%. ED was documented in all patients who had HAM/TSP,
in 79% of the group with EDSS 0 and 2, and in 35.9% of HTLV-1–infected individuals with
EDSS 0. OB was detected in 93.75%, 33.3%, and 4.6%, respectively. Moreover, there was an
association observed between ED and OB.
CONCLUSIONS ED is a frequent disease in HTLV-I-infected individuals, and the prevalence is directly correlated
to the degree of neurological disability measured by EDSS. ED was strongly associated with OB
|Description: ||Trabalho completo: acesso restrito, p.1100–1103|
|Appears in Collections:||Artigos Publicados em Periódicos (Medicina)|
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