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Use este identificador para citar ou linkar para este item: https://repositorio.ufba.br/handle/ri/5268
Tipo: Artigo de Periódico
Título: Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis and delay in starting antiretroviral therapy for AIDS patients
Título(s) alternativo(s): The Brazilian Journal of Infectious Diseases
Autor(es): Brites, Carlos
Martins Netto, Eduardo
Jorge, Célia Regina Mayoral Pedroso
Sampaio, Diana Brasil Pedral
Harrington Júnior, W.
Goyanna, F.
Adriano, S.
Autor(es): Brites, Carlos
Martins Netto, Eduardo
Jorge, Célia Regina Mayoral Pedroso
Sampaio, Diana Brasil Pedral
Harrington Júnior, W.
Goyanna, F.
Adriano, S.
Abstract: Objective: To compare the clinical characteristics and outcomes of HIV-1-HTLV-1 coinfected patients, in Bahia, Brazil. Methods: Retrospective, comparative study. Results: Among a total of 123 consecutive HIV infected patients, 20 men (20.6%) and 6 women (23.1%) had detectable antibodies against HTLV-I/II. The major risk factor associated with coinfection by HTLV was intravenous drug use (57.7% of coinfected patient versus 9.2% of HTLV seronegative patients, p < 0.0001). Coinfected patients had higher absolute lymphocyte counts (1,921 + 762 versus 1,587 + 951, p = 0.03). Both groups of patients had similar means of CD4+ and CD8+ cell counts. However, among patients with AIDS CD4+ cell counts were signifi cantly higher among those coinfected with HTLV-I/II (292 ± 92 cells/mm3, versus 140 ± 177cells/mm3, p = 0.36). The frequency and type of opportunistic infections were similar for both groups, but strongyloidiasis and encephalopathy were more frequently diagnosed in coinfected patients (p < 0.05). On the other hand, patients coinfected with HTLV-I/II received signifi cantly less antiretroviral therapy than singly infected by HIV-1. Conclusion: Coinfection by HTLV-I/II is associated with an increased risk of strongyloidiasis for HIV patients. Higher CD4 count may lead to underestimation of immunodefi ciency, and delay to initiate antiretroviral therapy.
Palavras-chave: HIV
HTLV-I/II
coinfection Strongyloidiasis
CD4/CD8
URI: http://www.repositorio.ufba.br/ri/handle/ri/5268
Data do documento: 2011
Aparece nas coleções:Artigo Publicado em Periódico Estrangeiro (ISC)

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