https://repositorio.ufba.br/handle/ri/14347
Tipo: | Artigo de Periódico |
Título: | Photochemical and pharmacological aspects of nitric oxide release from some nitrosyl ruthenium complexes entrapped in sol–gel and silicone matrices |
Título(s) alternativo(s): | Polyhedron |
Autor(es): | Lima, Renata Galvão de Sauaia, Marilia Gama Ferezin, Camila Pepe, Iuri Muniz José, Nadia Mamede Bendhack, Lusiane Maria Rocha, Zênis Novais da Silva, Roberto Santana da |
Autor(es): | Lima, Renata Galvão de Sauaia, Marilia Gama Ferezin, Camila Pepe, Iuri Muniz José, Nadia Mamede Bendhack, Lusiane Maria Rocha, Zênis Novais da Silva, Roberto Santana da |
Abstract: | The entrapped [Ru(terpy)(L)NO](PF6)3, where terpy = 2,2′:6′,2″-terpyridine and L = 2,2′-bipyridine (bpy) and 3,4-diiminebenzoic acid (NH · NHq) complexes into sol–gel processed polysiloxane and silicone matrices, shows NO release characteristics when submitted to light irradiation at 355 and 532 nm, as judged by NO measurement using a NO-sensor electrode. The pharmacological properties of doped matrix showed vasodilator characteristics by visible light irradiation, which is of great interest because the target delivery system can avoid the occurrence of side effects possibly by the aquo ruthenium species. All matrices obtained showed to be amorphous materials. The scanning electron micrographs of the matrices showed irregularly shaped particles, with a broad size of 1000 μm for both matrices and homogeneous distribution. |
Palavras-chave: | Immobilized ruthenium complexes Nitric oxide Photo-release |
Tipo de Acesso: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/14347 |
Data do documento: | 2007 |
Aparece nas coleções: | Artigo Publicado em Periódico (Química) |
Arquivo | Descrição | Tamanho | Formato | |
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1-s2.0-S0277538707002094-main.pdf | 284,16 kB | Adobe PDF | Visualizar/Abrir |
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