https://repositorio.ufba.br/handle/ri/14006
Tipo: | Artigo de Periódico |
Título: | Hospital-based surveillance of meningococcal meningitis in Salvador, Brazil |
Título(s) alternativo(s): | Trans. R. Soc. Trop. Med. Hyg |
Autor(es): | Cordeiro, Soraia Machado Neves, Alan B. Ribeiro, Cássio T. Petersen, Maya L. Gouveia, Edilane L. Ribeiro, Guilherme S., et al. |
Autor(es): | Cordeiro, Soraia Machado Neves, Alan B. Ribeiro, Cássio T. Petersen, Maya L. Gouveia, Edilane L. Ribeiro, Guilherme S., et al. |
Abstract: | This study aimed to describe the clinical, epidemiological and microbiological features of meningococcal meningitis in Salvador, Brazil. Between February 1996 and January 2001, a hospital based surveillance prospectively identified cases of culture-positive meningococcal meningitis. Demographic and clinical data were collected through interview and medical chart review. Antisera and monoclonal antibodies were used to determine the serogroup and serotype: serosubtype of the isolates, respectively. Surveillance identified a total of 408 cases of meningococcal meningitis, with a case fatality rate of 8% (32/397). The mean annual incidence for the 304 culture-positive cases residing in metropolitan Salvador was 1.71 cases per 100 000 population. Infants <1 year old presented the highest incidence (14.7 cases per 100 000 population). Of the 377 serogrouped isolates, 82%, 16%, 2% and 0.3% were serogroups B, C, W135 and Y, respectively. A single serotype:serosubtype (4,7:P1.19,15) accounted for 64% of all cases. Continued surveillance is necessary to characterise strains and to define future prevention and control strategies. |
Palavras-chave: | Meningococcal Disease Meningitis Neisseria Meningitidis Serogroup Epidemiology Brazil |
País: | Brasil |
Editora / Evento / Instituição: | Royal Society of Tropical Medicine and Hygiene Transactions |
Tipo de Acesso: | Acesso Aberto |
URI: | http://repositorio.ufba.br/ri/handle/ri/14006 |
Data do documento: | 2007 |
Aparece nas coleções: | Artigo Publicado em Periódico Estrangeiro (ISC) |
Arquivo | Descrição | Tamanho | Formato | |
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Guilherme Ribeiro. Hospital-based surveillance of meningococcal...2007.pdf | 302,03 kB | Adobe PDF | Visualizar/Abrir |
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