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Campo DC | Valor | Idioma |
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dc.contributor.author | Coutinho, Elsimar Metzker | - |
dc.contributor.author | Boulanger, G. Azadian | - |
dc.creator | Coutinho, Elsimar Metzker | - |
dc.creator | Boulanger, G. Azadian | - |
dc.date.accessioned | 2013-03-05T13:48:17Z | - |
dc.date.available | 2013-03-05T13:48:17Z | - |
dc.date.issued | 1984 | - |
dc.identifier.issn | 0020-7292 | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/8770 | - |
dc.description | Texto completo. Acesso restrito. p. 363-366 | pt_BR |
dc.description.abstract | Coutinho EM (Maternidade Climerio de Oliveira, Department of Maternal Health, Federal University of Bahia, School of Medicine, Salvador, Bahia, Brazil), Azadian- Boulanger G (Roussel-Uclaf, Paris, France). Treatment of fibrocystic disease of the breast with Gestrinone, a new trienic synthetic steroid with anti-estrogen, anti-progesterone properties. Int J Gynaecol Obstet 22: 363-366, 1984 Twenty-eight patients with radiologically diagnosed fibrocystic disease were given twice weekly 5 mg tablets of Gestrinone, asynthetic contraceptive steroid with potent antiestrogen , anti-progesterone properties, for periods ranging from 3 to 9 months. Treatment was discontinued when the nodularity disappeared and the patient became asymptomatic. Twelve patients had palpable nodules or masses in both breasts, while the remaining 16 had a single nodule or lump. In 12patients, all with small nodules or lumps, complete elimination of nodularity occurred at the end of the first 3 months of treatment. In a further eight patients, five of whom had small nodules and three of whom had large ones, an additional 3 months of therapy were required to achieve complete elimination of nodulan’ty. In two subjects, nodularity was eliminated at the end of 9 months of therapy, and in the remaining six subjects, although a reduction in nodularity greater than 50% occurred,masses remained palpable at the end of 9 months. Pain and tenderness were eliminated during the first 2 weeks of therapy in most cases. The most common complaints were acne and seborrhea (70% of patients) and a weight gain of between 2 and 5 kg in patients treated for 9 months. Main side effects encountered were acne and seborrhea. | pt_BR |
dc.language.iso | en | pt_BR |
dc.publisher | International Journal of Gynecology & Obstetrics | pt_BR |
dc.source | http://dx.doi.org/10.1016/0020-7292(84)90067-5 | pt_BR |
dc.subject | Gestrinone | pt_BR |
dc.subject | Fibrocystic disease | pt_BR |
dc.subject | Nodularity; | pt_BR |
dc.subject | Steroid | pt_BR |
dc.subject | Mammography | pt_BR |
dc.title | Treatment of fibrocystic disease of the breast with gestrinone, a new trienic synthetic steroid with anti-estrogen, anti-progesterone properties | pt_BR |
dc.title.alternative | International Journal of Gynecology & Obstetrics | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.description.localpub | Salvador | pt_BR |
dc.identifier.number | v. 22, n. 5 | pt_BR |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina) |
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