Intrauterine contraception with copper and with levonorgestrel: A randomized study of the TCu 380Ag and levonorgestrel 20 mcg/day devices

Abstract

Firsty ear resultso f a randomizeds tu% of 1509 usersof the Copper T38OAg with a silverc ore or of an IUD releasing2 0 mcg day of levonorgestrela re reported. The cumulativeg ross pregnanq rate for each device was 0.3 per 100 at one year, with more than 490 wcxnehna vingo ne year of use with each device. The levonorgestrel-releasidnegv ice was associatedw ith significantlyf ewer bleeding days and significantly increasedh emoglobinl evelsw hen ccmparedw ith pre-admissionv alues or the one year valueso bserveda morrugs erso f the lCu38OAg. 'Itxminations attributablteo amenorrheaw ere significantlmyo re frequenta mong users of the levonorgestre-lr eleasingd evice. 'IheT Cu 38OAgw as associated with increasedf requencya nd severity of dysmenorrheac ompared with pr~ac%nisaionl evels or with the steroid-releasidnegv ice. Hemoglobin levelsw ere sanewhatr eduoeda mong userso f the Ku 380Agd evice. I&- minations attributablet o pain were, however,n ot significantldyi fferentt y device. Continuatiorna tesa t the end of the firsty ear were not significantldyi fferentt y device.