Please use this identifier to cite or link to this item: https://repositorio.ufba.br/handle/ri/8099
metadata.dc.type: Artigo de Periódico
Title: Schistosoma mansoni infection and nutritional status in schoolchildren: a randomized, double-blind trial in northeastern Brazil
Other Titles: American Journal of Clinical Nutrition
Authors: Assis, Ana Marlucia de Oliveira
Barreto, Mauricio Lima
Prado, Matildes da Silva
Reis, Mitermayer G.
Parraga, Isabel M.
Blanton, Ronald Edward
metadata.dc.creator: Assis, Ana Marlucia de Oliveira
Barreto, Mauricio Lima
Prado, Matildes da Silva
Reis, Mitermayer G.
Parraga, Isabel M.
Blanton, Ronald Edward
Abstract: Brazilian schoolchildren with mild- to moderate- intensity schistosome infections (< 400 Schistosoma mansoni eggs/g stool) were randomly allocated to a treatment (oxamniquine) or placebo group in a double-blind fashion. Anthropometric measurements were made at baseline, 6 mo, and 1 y for 353 students. At baseline, the groups were not significantly different with respect to nutritional status or selected socioeconomic and biological characteristics, including anthropometric measures. One year later, significant differences were noted only in the nutritional status of boys treated for schistosome infection. Treated boys had greater measurements for weight, triceps skinfold thickness, midarm circumference, arm muscle area, and body mass index than untreated boys. They also showed significant increases over the year in weight, height, midarm circumference, and body mass index. The rates of improvement in weight and height were more accelerated in the first 6 mo after therapy than the last. These results indicate that, at least in boys, chronic S. mansoni infection at any intensity is detrimental to short-term growth and development.
Keywords: Schistosoma mansoni
growth
sex
oxamniquine
morbidity
therapy
anthropometry
parasitic infection
schoolchildren
URI: http://www.repositorio.ufba.br/ri/handle/ri/8099
Issue Date: 1998
Appears in Collections:Artigo Publicado em Periódico (Escola de Nutrição)

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