https://repositorio.ufba.br/handle/ri/7884
metadata.dc.type: | Artigo de Periódico |
Título : | Vaginal colonization by Candida in asymptomatic women with and without a history of recurrent vulvovaginal candidiasis |
Otros títulos : | Obstetrics and Gynecology |
Autor : | Giraldo, Paulo Nowaskonski, Angele von Gomes, Francis A. M. Linhares, Iara Neves, Nilma Antas Witkin, Steven S. |
metadata.dc.creator: | Giraldo, Paulo Nowaskonski, Angele von Gomes, Francis A. M. Linhares, Iara Neves, Nilma Antas Witkin, Steven S. |
Resumen : | Objective: The asymptomatic carriage of Candida in the vagina of women with a history of recurrent vulvovaginal candidiasis was compared with that of women with no such history. Methods: Vaginal swabs from 50 women with a history of recurrent vulvovaginal candidiasis and 45 women with one or fewer episodes of candidal vaginaitis within the past 12 months were evaluated for Candida by wet mount/Gram stain, culture, and polymerase chain reaction (PCR). All women were asymptomatic for at least 30 days. Results: Candida was identified in 28 women by PCR, in 14 women by culture, and in 13 women by wet mount/Gram stain. Candida was identified by PCR in a similar proportion of patients with previous recurrent vulvovaginal candidiasis (30%) and in controls (28.8%). However, Candida was identified by culture in more women with previous recurrent vulvovaginal candidiasis (22%) than in controls (6.6%, P = .04); it also was identified by wet mount/Gram stain in more women with recurrent vulvovaginal candidiasis (22%) than in controls (4.4%, P = .01). For the recurrent vulvovaginal candidiasis patients, culture and wet mount/Gram stain had a sensitivity of 66.6% compared with PCR. For the controls, the sensitivity of the two former assays relative to PCR was only 15.3%. conclusion: Women with a history of recurrent vulvovaginal candidiasis have more easily detectable Candida in their vagina, even when asymptomatic, than do other women. A relative inefficiency in regulating the proliferation of Candida in the vagina may increase susceptibility to periodic symptomatic recurrences. |
URI : | http://www.repositorio.ufba.br/ri/handle/ri/7884 |
Fecha de publicación : | mar-2000 |
Aparece en las colecciones: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Fichero | Descripción | Tamaño | Formato | |
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Giraldo.pdf Restricted Access | 284,6 kB | Adobe PDF | Visualizar/Abrir Request a copy |
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