https://repositorio.ufba.br/handle/ri/7745
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Moran, Alison J. | - |
dc.contributor.author | Treit, Janice D. | - |
dc.contributor.author | Whitney, Janice L. | - |
dc.contributor.author | Abomoelak, Bassam | - |
dc.contributor.author | Sampaio, Diana Pedral | - |
dc.contributor.author | Badaró, Roberto José da Silva | - |
dc.creator | Moran, Alison J. | - |
dc.creator | Treit, Janice D. | - |
dc.creator | Whitney, Janice L. | - |
dc.creator | Abomoelak, Bassam | - |
dc.creator | Sampaio, Diana Pedral | - |
dc.creator | Badaró, Roberto José da Silva | - |
dc.date.accessioned | 2013-01-04T12:49:34Z | - |
dc.date.issued | 2001 | - |
dc.identifier.issn | 0378-1097 | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/7745 | - |
dc.description | Texto completo: acesso restrito. p. 31–36 | pt_BR |
dc.description.abstract | To identify antigens that would improve the accuracy of serological diagnosis of active tuberculosis, we cloned the genes encoding nine potentially immunogenic secreted or surface-associated proteins of Mycobacterium tuberculosis. Recombinant proteins were reacted with sera from HIV-negative individuals with extrapulmonary tuberculosis (EP-TB) or HIV-positive individuals with pulmonary tuberculosis (TBH). Specific and high level antibody responses were obtained for four recombinant proteins, of which antigen GST-822 was recognized by 60% of EP-TB and 42% of TBH and antigen MBP-506 was recognized by 45% of EP-TB and 61% of TBH. These results suggest that these proteins are strong candidates as subunits in a polyvalent serodiagnostic test. | pt_BR |
dc.language.iso | en | pt_BR |
dc.source | http://dx.doi.org/10.1016/S0378-1097(01)00115-X | pt_BR |
dc.subject | Serodiagnosis | pt_BR |
dc.subject | Tuberculosis | pt_BR |
dc.subject | Antigen | pt_BR |
dc.title | Assessment of the serodiagnostic potential of nine novel proteins from Mycobacterium tuberculosis | pt_BR |
dc.title.alternative | FEMS Microbiology Letters | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.identifier.number | v. 198, n. 1 | pt_BR |
dc.embargo.liftdate | 10000-01-01 | - |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Arquivo | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Moran.pdf Restricted Access | 243,87 kB | Adobe PDF | Visualizar/Abrir Solicitar uma cópia |
Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.