Campo DC | Valor | Idioma |
dc.contributor.author | Reis, Sílvia Regina de Almeida | - |
dc.contributor.author | Espírito Santo, Alexandre Ribeiro do | - |
dc.contributor.author | Andrade, Miguel Gustavo Setúbal | - |
dc.contributor.author | Sadigursky, Moysés | - |
dc.creator | Reis, Sílvia Regina de Almeida | - |
dc.creator | Espírito Santo, Alexandre Ribeiro do | - |
dc.creator | Andrade, Miguel Gustavo Setúbal | - |
dc.creator | Sadigursky, Moysés | - |
dc.date.accessioned | 2012-10-22T21:05:17Z | - |
dc.date.available | 2012-10-22T21:05:17Z | - |
dc.date.issued | 2006-04 | - |
dc.identifier.issn | 1806-8324 | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/7026 | - |
dc.description | p.97-102 | pt_BR |
dc.description.abstract | The effects of ethanol alone on the oral mucosa are still poorly understood, especially because there are few non-smoking chronic consumers of alcoholic beverages. The aim of this study was to evaluate the frequency of micronucleus, abnormal nucleus/cytoplasm ratio, pyknosis, karyorrhexis and karyolysis in exfoliated cells from the buccal mucosa and from the lateral border of the tongue in 36 non-smoker alcoholics (ethanol group) and 18 non-smokers and non-drinkers (control group). The Papanicolaou method was used. Since alcoholics generally have hepatobiliary involvement, the association between serum gamma-glutamyl transpeptidase (GGT) and some of the analyzed oral mucosa alterations was also investigated. The ethanol group showed a significant increase in the frequency of all alterations analyzed in the tongue cells when compared with the control group (p < 0.01; Mann-Whitney). However, the presence of these changes in buccal mucosa cells was not statistically significant (p > 0.05; Mann-Whitney). In the ethanol group, the correlation between serum GGT and the frequency of micronucleus and abnormal nucleus/cytoplasm ratio in oral mucosa cells was not significant (p > 0.05; Spearman). In conclusion, chronic exposure to ethanol may be associated with carcinogenic cytologic changes in the oral mucosa, even in the absence of tobacco smoking. These alterations were not correlated with hepatobiliary injury. | pt_BR |
dc.language.iso | en | pt_BR |
dc.publisher | Sociedade Brasileira de Pesquisa Odontológica | pt_BR |
dc.source | http://dx.doi.org/10.1590/S1806-83242006000200002 | pt_BR |
dc.subject | Cytology | pt_BR |
dc.subject | Mouth mucosa | pt_BR |
dc.subject | Ethanol | pt_BR |
dc.subject | Carcinogens | pt_BR |
dc.title | Cytologic alterations in the oral mucosa after chronic exposure to ethanol | pt_BR |
dc.title.alternative | Brazilian Oral Research | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.description.localpub | São Paulo | pt_BR |
dc.identifier.number | v. 20, n. 2 | pt_BR |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Odontologia)
|