Campo DC | Valor | Idioma |
dc.contributor.author | Miranda, Maria da Pureza Spínola | - |
dc.contributor.author | Cintra, R. G. | - |
dc.contributor.author | Barros, S. B. M. | - |
dc.contributor.author | Mancini Filho, J. | - |
dc.creator | Miranda, Maria da Pureza Spínola | - |
dc.creator | Cintra, R. G. | - |
dc.creator | Barros, S. B. M. | - |
dc.creator | Mancini Filho, J. | - |
dc.date.accessioned | 2012-10-17T12:11:35Z | - |
dc.date.available | 2012-10-17T12:11:35Z | - |
dc.date.issued | 1998 | - |
dc.identifier.issn | 1414-431X | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/6973 | - |
dc.description | p. 1075-1079 | pt_BR |
dc.description.abstract | Spirulina maxima, which is used as a food additive, is a microalga rich in protein and other essential nutrients. Spirulina contains phenolic acids, tocopherols and ß-carotene which are known to exhibit antioxidant properties. The aim of the present study was to evaluate the antioxidant capacity of a Spirulina extract. The antioxidant activity of a methanolic extract of Spirulina was determined in vitro and in vivo. The in vitro antioxidant capacity was tested on a brain homogenate incubated with and without the extract at 37oC. The IC50 (concentration which causes a 50% reduction of oxidation) of the extract in this system was 0.18 mg/ml. The in vivo antioxidant capacity was evaluated in plasma and liver of animals receiving a daily dose of 5 mg for 2 and 7 weeks. Plasma antioxidant capacity was measured in brain homogenate incubated for 1 h at 37oC. The production of oxidized compounds in liver after 2 h of incubation at 37oC was measured in terms of thiobarbituric acid reactant substances (TBARS) in control and experimental groups. Upon treatment, the antioxidant capacity of plasma was 71% for the experimental group and 54% for the control group. Data from liver spontaneous peroxidation studies were not significantly different between groups. The amounts of phenolic acids, a-tocopherol and ß-carotene were determined in Spirulina extracts. The results obtained indicate that Spirulina provides some antioxidant protection for both in vitro and in vivo systems. | pt_BR |
dc.language.iso | en | pt_BR |
dc.source | http://dx.doi.org/10.1590/S0100-879X1998000800007 | pt_BR |
dc.subject | microalgae | pt_BR |
dc.subject | antioxidant activity | pt_BR |
dc.subject | Spirulina maxima | pt_BR |
dc.subject | phenolic compounds | pt_BR |
dc.subject | ß-carotene | pt_BR |
dc.subject | a-tocopherol | pt_BR |
dc.title | Antioxidant activity of the microalga Spirulina maxima | pt_BR |
dc.title.alternative | Brazilian Journal of Medical and Biological Research | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.description.localpub | Ribeirão Preto | pt_BR |
dc.identifier.number | v. 31, n. 8 | pt_BR |
Aparece nas coleções: | Artigo Publicado em Periódico (FAR)
|