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https://repositorio.ufba.br/handle/ri/6965
Full metadata record
DC Field | Value | Language |
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dc.contributor.author | Lyra, André Castro | - |
dc.contributor.author | Fan, X. | - |
dc.contributor.author | Di Bisceglie, A. M. | - |
dc.creator | Lyra, André Castro | - |
dc.creator | Fan, X. | - |
dc.creator | Di Bisceglie, A. M. | - |
dc.date.accessioned | 2012-10-16T20:08:25Z | - |
dc.date.available | 2012-10-16T20:08:25Z | - |
dc.date.issued | 2004 | - |
dc.identifier.issn | 0100-879X | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/6965 | - |
dc.description | p. 691-695 | pt_BR |
dc.description.abstract | Hepatitis C virus (HCV) was first described in 1989 as the putative viral agent of non-A non-B hepatitis. It is a member of the Flaviviridae family and has been recognized as the major causative agent of chronic liver disease, including chronic active hepatitis, cirrhosis and hepatocellular carcinoma. HCV is a positive RNA virus with a genome containing approximately 9500 nucleotides. It has an open reading frame that encodes a large polyprotein of about 3000 amino acids and is characterized by extensive genetic diversity. HCV has been classified into at least 6 major genotypes with many subtypes and circulates within an infected individual as a number of closely related but distinct variants known as quasispecies. This article reviews aspects of the molecular biology of HCV and their clinical implication. | pt_BR |
dc.language.iso | en | pt_BR |
dc.publisher | Brazilian Journal of Medical and Biological Research | pt_BR |
dc.title | Molecular biology and clinical implication of hepatitis C virus | pt_BR |
dc.title.alternative | Brazilian Journal of Medical and Biological Research | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.description.localpub | Salvador | pt_BR |
Appears in Collections: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Files in This Item:
File | Description | Size | Format | |
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Lyra, A.C.,.pdf | 487,4 kB | Adobe PDF | View/Open |
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