Use este identificador para citar ou linkar para este item:
https://repositorio.ufba.br/handle/ri/6897
Registro completo de metadados
Campo DC | Valor | Idioma |
---|---|---|
dc.contributor.author | Focaccia, R. | - |
dc.contributor.author | Baraldo, D. C. M. | - |
dc.contributor.author | Ferraz, M. L. G. | - |
dc.contributor.author | Martinelli, A. L. C. | - |
dc.contributor.author | Carrilho, F. J. | - |
dc.contributor.author | Gonçales Júnior, F. L. | - |
dc.contributor.author | Pedroso, M. L. A. | - |
dc.contributor.author | Coelho, H. S. M. | - |
dc.contributor.author | Lacerda, M. A. | - |
dc.contributor.author | Brandão, C. E. | - |
dc.contributor.author | Mattos, A. A. | - |
dc.contributor.author | Lira, L. G. C. | - |
dc.contributor.author | Zamin Júnior, I. | - |
dc.contributor.author | Pinheiro, J. O. P. | - |
dc.contributor.author | Tovo, C. V. | - |
dc.contributor.author | Both, C. T. | - |
dc.contributor.author | Soares, J. A. S. | - |
dc.contributor.author | Dittrich, S. | - |
dc.creator | Focaccia, R. | - |
dc.creator | Baraldo, D. C. M. | - |
dc.creator | Ferraz, M. L. G. | - |
dc.creator | Martinelli, A. L. C. | - |
dc.creator | Carrilho, F. J. | - |
dc.creator | Gonçales Júnior, F. L. | - |
dc.creator | Pedroso, M. L. A. | - |
dc.creator | Coelho, H. S. M. | - |
dc.creator | Lacerda, M. A. | - |
dc.creator | Brandão, C. E. | - |
dc.creator | Mattos, A. A. | - |
dc.creator | Lira, L. G. C. | - |
dc.creator | Zamin Júnior, I. | - |
dc.creator | Pinheiro, J. O. P. | - |
dc.creator | Tovo, C. V. | - |
dc.creator | Both, C. T. | - |
dc.creator | Soares, J. A. S. | - |
dc.creator | Dittrich, S. | - |
dc.date.accessioned | 2012-10-08T19:44:50Z | - |
dc.date.available | 2012-10-08T19:44:50Z | - |
dc.date.issued | 2004-10 | - |
dc.identifier.issn | 1413-8670 | - |
dc.identifier.uri | http://www.repositorio.ufba.br/ri/handle/ri/6897 | - |
dc.description | p.348-355 | pt_BR |
dc.description.abstract | Hepatitis C virus (HCV) infection is a serious public health problem, since 80% to 85% of HCV carriers develop a persistent infection that can progress into liver cirrhosis and hepatocarcinoma. Considering that the response of hepatitis C patients to combination therapy with interferon and ribavirin depends on HCV characteristics as well as on host features, we made a retrospective analysis of demographic and anthropometrical data and HCV genotype distribution of chronic hepatitis C patients treated in public and private reference centers in Brazil. The medical records of 4,996 patients were reviewed, 81% from public and 19% from private institutions. Patients' median age was 46 years, and there was a higher prevalence of male (62%) and white patients (80%). The analysis of HCV-infecting strains showed a predominance of genotype 1 (64%) over genotypes 2 and 3. The patients' mean weight was 70.6 kg, and 65% of the patients weighed less than 77kg. Overweight and obesity were observed in 37.8% and 13.6% of the patients, respectively. Since a body weight of 75 kg or less has been considered an independent factor that significantly increases the odds of achieving a sustained virological response, the Brazilian population seems to have a more favorable body weight profile to achieve a sustained response than the American and European populations. The finding that 65% of chronic hepatitis C patients have a body weight of 77 kg or less may have a positive pharmacoeconomic impact on the treatment of genotype 1 HCV patients with weight-based doses of peginterferon. | pt_BR |
dc.language.iso | en | pt_BR |
dc.publisher | The Brazilian Journal of Infectious Diseases and Contexto Publishing | pt_BR |
dc.source | http://dx.doi.org/10.1590/S1413-86702004000500003 | pt_BR |
dc.subject | HCV | pt_BR |
dc.subject | Chronic hepatitis C | pt_BR |
dc.subject | Genotype | pt_BR |
dc.subject | Body weight | pt_BR |
dc.subject | Brazil | pt_BR |
dc.title | Demographic and anthropometrical analysis and genotype distribution of chronic hepatitis C patients treated in public and private reference centers in Brazil | pt_BR |
dc.title.alternative | Brazilian Journal of Infectious Diseases | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.description.localpub | Salvador | pt_BR |
dc.identifier.number | v. 8, n. 5 | pt_BR |
Aparece nas coleções: | Artigo Publicado em Periódico (Faculdade de Medicina) |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
---|---|---|---|---|
Focaccia, R..pdf | 153,52 kB | Adobe PDF | Visualizar/Abrir |
Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.