Please use this identifier to cite or link to this item:
Full metadata record
DC FieldValueLanguage
dc.contributor.authorAlves, Crésio de Aragão Dantas-
dc.contributor.authorVieira, Nara-
dc.contributor.authorMeyer, Isadora-
dc.contributor.authorAlves, Cândida Oliveira-
dc.contributor.authorToralles, Maria Betânia Pereira-
dc.contributor.authorOliveira, Maria de Fátima Santos Paim de-
dc.creatorAlves, Crésio de Aragão Dantas-
dc.creatorVieira, Nara-
dc.creatorMeyer, Isadora-
dc.creatorAlves, Cândida Oliveira-
dc.creatorToralles, Maria Betânia Pereira-
dc.creatorOliveira, Maria de Fátima Santos Paim de-
dc.description.abstractThe participation of the human histocompatibility system (HLA: human leukocyte antigens) in the pathogenesis of autoimmune diseases is well known. Situated on the short arm of chromosome 6, the HLA system is very polymorphic and has the capacity to confer susceptibility or resistance to different diseases. In Dermatology, this system has an important participation in the pathogenesis and natural course of various diseases. The strength and type of association differ with conditions and sometimes with the ethnic-racial group studied. The discovery of molecular methods to typify HLA alleles and recent updates in its nomenclature has contributed to a better understanding of this system. Unfortunately, this information has not been adequately transmitted in the literature, hindering identification of the association of the HLA with skin diseases. In this review, some aspects of the HLA system are discussed, such as methods of detection, nomenclature and association with vitiligo, pemphigus, psoriasis, lupus erythematosus, scabies, cutaneous Leishmaniasis, leprosy, paracoccidiodomycosis and atopic dermatitis.pt_BR
dc.publisherSociedade Brasileira de Dermatologiapt_BR
dc.subjectHLA antigenspt_BR
dc.subjectMajor histocompatibility complexpt_BR
dc.subjectSkin diseasespt_BR
dc.titleHuman histocompatibility antigens and Dermatology: from research to clinical practicept_BR
dc.title.alternativeAnais Brasileiros de Dermatologiapt_BR
dc.typeArtigo de Periódicopt_BR
dc.description.localpubRio de Janeiropt_BR
dc.identifier.numberv. 81, n. 1pt_BR
Appears in Collections:Artigo Publicado em Periódico (Faculdade de Medicina)

Files in This Item:
File Description SizeFormat 
Alves, Crésio.pdf_2120,6 kBAdobe PDFView/Open

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.