https://repositorio.ufba.br/handle/ri/4799
metadata.dc.type: | Artigo de Periódico |
Title: | Risk Factors for Human T Cell Lymphotropic Virus Type I among Injecting Drug Users in Northeast Brazil: Possibly Greater Efficiency of Male to Female Transmission |
Other Titles: | Memórias do Instituto Oswaldo Cruz |
Authors: | Dourado, Maria Inês Costa Andrade, Tarcísio Matos de Carpenter, Catherine L. Castro, Bernardo Galvão |
metadata.dc.creator: | Dourado, Maria Inês Costa Andrade, Tarcísio Matos de Carpenter, Catherine L. Castro, Bernardo Galvão |
Abstract: | It was observed in the city of Salvador, State of Bahia, the highest seroprevalence of human T cell lymphotropic virus type 1 (HTLV-I) infection in Brazil as demonstrated by national wide blood bank surveys. In this paper, we report results of an investigation of drug use and sexual behavior associated with HTLV-I infection among male and female injecting drug users (IDUs) in Salvador. A cross sectional study was conducted in the Historical District of Salvador from 1994-1996 (Projeto Brasil-Salvador) and 216 asymptomatic IDUs were selected using the snowball contact technique. Blood samples were collected for serological assays. Sera were screened for human immunodeficiency virus (HIV-1/2) and HTLV-I/II antibodies by ELISA and confirmed by Western blot. The overall prevalence of HTLV-I/ II was 35.2% (76/216). The seroprevalence of HTLV-I, HTLV-II and HIV-1 was for males 22%, 11.3% and 44.1% and for females 46.2%, 10.3% and 74.4% respectively. HTLV-I was identified in 72.4% of HTLV positive IDUs. Variables which were significantly associated with HTLV-I infection among males included needle sharing practices, duration of injecting drug use, HIV-1 seropositivity and syphilis. Among women, duration of injecting drug use and syphilis were strongly associated with HTLV-I infection. Multivariate analysis did not change the direction of these associations. Sexual intercourse might play a more important role in HTLV-I infection among women than in men. |
Keywords: | human T cell lymphotropic virus type I/II (HTLV-I/II) human immunodeficiency virus type 1 (HIV-1) injecting drug use snowball sampling Bahia Brazil |
URI: | http://www.repositorio.ufba.br/ri/handle/ri/4799 |
Issue Date: | 1999 |
Appears in Collections: | Artigo Publicado em Periódico Nacional (ISC) |
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