https://repositorio.ufba.br/handle/ri/42676| Campo DC | Valor | Idioma |
|---|---|---|
| dc.creator | Nascimento, Mariana Santana | - |
| dc.date.accessioned | 2025-08-06T19:10:38Z | - |
| dc.date.available | 2027-06-06 | - |
| dc.date.available | 2025-08-06T19:10:38Z | - |
| dc.date.issued | 2025-05-30 | - |
| dc.identifier.citation | NASCIMENTO, Mariana Santana. Técnicas de terapia manual no manejo da constipação funcional: uma revisão sistemática com metanálise. Orientadora: Karen Valadares Trippo. 2025. 71 f. Dissertação (Mestrado em Ciências da Reabilitação) - Instituto Multidisciplinar de Reabilitação e Saúde, Universidade Federal da Bahia, Salvador (BA), 2025. | pt_BR |
| dc.identifier.uri | https://repositorio.ufba.br/handle/ri/42676 | - |
| dc.description.abstract | Introduction: Functional constipation (FC) is a prevalent gastrointestinal disorder affecting patients' quality of life and causing difficulty evacuating. Among the therapeutic resources used by physiotherapy to treat functional constipation, manual therapy (MT) techniques are low-cost approaches and can be performed by the patient himself, if he is properly guided. Despite the good performance of abdominal massage in FC, previous systematic review studies do not gather the possible MT techniques in managing constipation. In addition, there is a lack of systematic studies with meta-analysis that evaluate the effectiveness of different MT techniques in the severity of FC and the quality of life of people affected by this dysfunction. Objective: To evaluate the effectiveness of manual therapy techniques in managing functional constipation. Method: Systematic Review with Meta-Analysis by the PRISMA recommendations. Clinical trials were selected from the following databases: National Library of Medicine (PUBMED/MedLine), EMBASE (Elsevier), Physiotherapy Evidence Database (PEDro), and Biblioteca Virtual de Saúde (BVS), with no restrictions on language or year of publication. The meta-analysis used Reviewer Manager V.5.4. Results: Forty-one studies were included. The results of a subgroup analysis with MT types showed that abdominal massage reduced the severity of constipation and improved quality of life in all comparisons, except with medications, with a mean difference (MD) in severity of 0.16 (95% CI: -6.92 to 7.24, p=0.96); while aromatic abdominal massage only showed a significant effect in the comparison versus control on the outcome quality of life, with an MD of -12.05 (-21.96, -16.14, p<0.00001). Acupressure showed a positive effect on both outcomes evaluated. Osteopathic manipulation demonstrated a positive impact on symptom severity when compared with other therapies or placebo. Conclusion: There is very low to moderate quality evidence that abdominal massage and acupressure, showed more significant results in improving the severity of functional constipation and quality of life. Abdominal meridian massage, osteopathic manipulation, and foot reflexology showed positive effects only on the outcome of constipation severity, whereas aromatic abdominal massage demonstrated benefits solely on the outcome of quality of life. | pt_BR |
| dc.description.sponsorship | Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB) | pt_BR |
| dc.language | por | pt_BR |
| dc.publisher | Universidade Federal da Bahia | pt_BR |
| dc.rights | Acesso Restrito/Embargado | pt_BR |
| dc.subject | Constipação intestinal | pt_BR |
| dc.subject | Constipação Funcional | pt_BR |
| dc.subject | Terapia manual | pt_BR |
| dc.subject | Manipulações Musculoesqueléticas | pt_BR |
| dc.subject | Fisioterapia | pt_BR |
| dc.subject.other | Constipation | pt_BR |
| dc.subject.other | Functional Constipation | pt_BR |
| dc.subject.other | Manual Therapy | pt_BR |
| dc.subject.other | Musculoskeletal Manipulations | pt_BR |
| dc.subject.other | Physical Therapy | pt_BR |
| dc.title | Técnicas de terapia manual no manejo da constipação funcional: uma revisão sistemática com metanálise | pt_BR |
| dc.title.alternative | Manual therapy techniques in the management of functional constipation: a systematic review with meta-analysis | pt_BR |
| dc.type | Dissertação | pt_BR |
| dc.publisher.program | Programa de Pós Graduação em Ciências da Reabilitação (PPGREAB) | pt_BR |
| dc.publisher.initials | UFBA | pt_BR |
| dc.publisher.country | Brasil | pt_BR |
| dc.subject.cnpq | CNPQ::CIENCIAS DA SAUDE::FISIOTERAPIA E TERAPIA OCUPACIONAL | pt_BR |
| dc.contributor.advisor1 | Trippo, Karen Valadares | - |
| dc.contributor.advisor1ID | https://orcid.org/0000-0002-0182-0129 | pt_BR |
| dc.contributor.advisor1Lattes | http://lattes.cnpq.br/7077622397421377 | pt_BR |
| dc.contributor.referee1 | Trippo, Karen Valadares | - |
| dc.contributor.referee1ID | https://orcid.org/0000-0002-0182-0129 | pt_BR |
| dc.contributor.referee1Lattes | http://lattes.cnpq.br/7077622397421377 | pt_BR |
| dc.contributor.referee2 | Januário, Priscila Godoy | - |
| dc.contributor.referee2Lattes | http://lattes.cnpq.br/6292136102412500 | pt_BR |
| dc.contributor.referee3 | Santos, Cleber Luz | - |
| dc.contributor.referee3Lattes | http://lattes.cnpq.br/1351352771153286 | pt_BR |
| dc.creator.Lattes | http://lattes.cnpq.br/7448976064588011 | pt_BR |
| dc.description.resumo | Introdução: Constipação funcional (CF) é um distúrbio gastrointestinal prevalente que afeta a qualidade de vida dos pacientes, os quais passam a conviver com a dificuldade de evacuar. Entre os recursos terapêuticos utilizados pela fisioterapia no tratamento da constipação funcional, as técnicas de terapia manual (TM) são abordagens consideradas de baixo custo e que podem ser realizadas pelo próprio paciente, desde que devidamente orientados. Apesar do bom desempenho da massagem abdominal na CF, estudos de revisão sistemática prévios não reúnem as técnicas de TM possíveis no manejo da constipação. Além disso, há uma escassez de estudos sistemáticos com metanálise que avaliem a efetividade de diferentes técnicas de TM na gravidade da CF e na qualidade de vida de pessoas acometidas por essa disfunção. Objetivo: Avaliar a efetividade das técnicas de terapias manuais no manejo da constipação funcional. Método: Revisão Sistemática com Metanálise em conformidade às recomendações PRISMA. Os ensaios clínicos foram selecionados nas bases de dados: National Library of Medicine (PUBMED/ MedLine), EMBASE (Elsevier), Physiotherapy Evidence Data base (PEDro) e Bibliotera Virtual de Saúde (BVS), sem restrições de linguagem ou de ano de publicação. A metanálise foi conduzida usando o Reviewer Manager V.5.4. Resultados: Foram incluídos 41 estudos. Os resultados de uma análise de subgrupo com os tipos de TM mostraram que a massagem abdominal reduziu a gravidade da constipação e melhorou a qualidade de vida em todas as comparações, exceto com medicamentos, com diferença média (MD) na gravidade de 0,16 (IC 95%: -6,92 a 7,24, p=0,96); enquanto a massagem abdominal aromática somente apresentou efeito significativo na comparação versus controle no desfecho qualidade de vida com MD de -12.05 (-21.96, -16,14, p<0,00001). Acupressão apresentou efeito positivo em ambos os desfechos avaliados. Manipulação osteopática demonstrou efeito positivo na gravidade dos sintomas quando comparada com outras terapias ou placebo. Conclusão: Há evidências de muito baixa a moderada qualidade de que a massagem abdominal e a acupressão apresentaram resultados mais significativos na melhora da gravidade da constipação funcional e na qualidade de vida. A massagem meridiana abdominal, manipulação osteopática e reflexologia podal apresentaram efeitos positivos apenas no desfecho gravidade da constipação, enquanto que, a massagem abdominal aromática demonstrou benefício apenas no desfecho qualidade de vida. | pt_BR |
| dc.publisher.department | Instituto Multidisciplinar de Reabilitação e Saúde (IMRS) | pt_BR |
| dc.relation.references | ANDREWS, C. N.; STORR, M. The pathophysiology of chronic constipationCan J Gastroenterol. [s.l: s.n.]. ANTUNES, M. D. et al. Constipação intestinal em idosos e a relação com atividade física, alimentação e cognição. Revista de Medicina, v. 98, n. 3, p. 202–207, 22 jul. 2019. AYDEMIR, T. et al. The effect of acupressure on constipation symptoms and quality of life among older people: a mixed-methods study. European Geriatric Medicine, v. 14, n. 5, p. 1135–1144, 1 out. 2023. AYDINLI, A.; KARADAĞ, S. “Effects of abdominal massage applied with ginger and lavender oil for elderly with constipation: A randomized controlled trial”. Explore, v. 19, n. 1, p. 115–120, 1 jan. 2023. AZIZ, A.; RAO, S. S. C. Emerging Treatments for Chronic Constipation And Defecation Disorders. GASTROENTEROLOGY & ENDOSCOPY NEWS, p. 1–12, maio 2024. AZIZ, I. et al. An approach to the diagnosis and management of Rome IV functional disorders of chronic constipation. Expert Review of Gastroenterology and HepatologyTaylor and Francis Ltd, , 2 jan. 2020. BARAN, A.; ATES, S. The Effects of Abdominal Massage in the Management of Constipation in Elderly People: A Randomized Controlled Study. Topics in Geriatric Rehabilitation, v. 35, n. 2, p. 134–140, 1 abr. 2019. BOAS FERNANDES, W. V. et al. Effect of osteopathic visceral manipulation for individuals with functional constipation and chronic nonspecific low back pain: Randomized controlled trial. Journal of Bodywork and Movement Therapies, v. 34, p. 96–103, 1 abr. 2023. BUFFONE, F. et al. Effectiveness of Osteopathic Manipulative Treatment in Adults with Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis. Healthcare (Switzerland)Multidisciplinary Digital Publishing Institute (MDPI), , 1 set. 2023. CHATIP, A. T.; ACAR, G.; AKÇAY, A. A. Comparison of the effects of abdominal massage and osteopathic manipulative treatment home program on constipation in children with cerebral palsy. JGH Open, v. 8, n. 6, 1 jun. 2024. CONNOR, M. et al. Using abdominal massage in bowel management. Arte e Ciência. Padrão enfermagem, v. 28, n. 45, p. 37–42, 2014. DADURA, E. et al. Effects of abdominal massage on constipation in palliative care patients - A pilot study. Postepy Rehabilitacji, v. 31, n. 4, p. 19–34, 1 dez. 2017. DOǦAN, I. G. et al. Abdominal Massage in Functional Chronic Constipation: A Randomized Placebo-Controlled Trial. Physical Therapy, v. 102, n. 7, 1 jul. 2022. DROUIN, J. S. et al. Comparisons between manual lymph drainage, abdominal massage, and electrical stimulation on functional constipation outcomes: A randomized, controlled trial. International Journal of Environmental Research and Public Health, v. 17, n. 11, 1 jun. 2020. 58 ANDREWS, C. N.; STORR, M. The pathophysiology of chronic constipationCan J Gastroenterol. [s.l: s.n.]. ANTUNES, M. D. et al. Constipação intestinal em idosos e a relação com atividade física, alimentação e cognição. Revista de Medicina, v. 98, n. 3, p. 202–207, 22 jul. 2019. AYDEMIR, T. et al. The effect of acupressure on constipation symptoms and quality of life among older people: a mixed-methods study. European Geriatric Medicine, v. 14, n. 5, p. 1135–1144, 1 out. 2023. AYDINLI, A.; KARADAĞ, S. “Effects of abdominal massage applied with ginger and lavender oil for elderly with constipation: A randomized controlled trial”. Explore, v. 19, n. 1, p. 115–120, 1 jan. 2023. AZIZ, A.; RAO, S. S. C. Emerging Treatments for Chronic Constipation And Defecation Disorders. GASTROENTEROLOGY & ENDOSCOPY NEWS, p. 1–12, maio 2024. AZIZ, I. et al. An approach to the diagnosis and management of Rome IV functional disorders of chronic constipation. Expert Review of Gastroenterology and HepatologyTaylor and Francis Ltd, , 2 jan. 2020. BARAN, A.; ATES, S. The Effects of Abdominal Massage in the Management of Constipation in Elderly People: A Randomized Controlled Study. Topics in Geriatric Rehabilitation, v. 35, n. 2, p. 134–140, 1 abr. 2019. BOAS FERNANDES, W. V. et al. Effect of osteopathic visceral manipulation for individuals with functional constipation and chronic nonspecific low back pain: Randomized controlled trial. Journal of Bodywork and Movement Therapies, v. 34, p. 96–103, 1 abr. 2023. BUFFONE, F. et al. Effectiveness of Osteopathic Manipulative Treatment in Adults with Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis. Healthcare (Switzerland)Multidisciplinary Digital Publishing Institute (MDPI), , 1 set. 2023. CHATIP, A. T.; ACAR, G.; AKÇAY, A. A. Comparison of the effects of abdominal massage and osteopathic manipulative treatment home program on constipation in children with cerebral palsy. JGH Open, v. 8, n. 6, 1 jun. 2024. CONNOR, M. et al. Using abdominal massage in bowel management. Arte e Ciência. Padrão enfermagem, v. 28, n. 45, p. 37–42, 2014. DADURA, E. et al. Effects of abdominal massage on constipation in palliative care patients - A pilot study. Postepy Rehabilitacji, v. 31, n. 4, p. 19–34, 1 dez. 2017. DIRETRIZES METODOLÓGICAS Sistema GRADE-manual de graduação da qualidade da evidência e força de recomendação para tomada de decisão em saúde. . [s.l: s.n.]. DOǦAN, I. G. et al. Abdominal Massage in Functional Chronic Constipation: A Randomized Placebo-Controlled Trial. Physical Therapy, v. 102, n. 7, 1 jul. 2022. 59 DROUIN, J. S. et al. Comparisons between manual lymph drainage, abdominal massage, and electrical stimulation on functional constipation outcomes: A randomized, controlled trial. International Journal of Environmental Research and Public Health, v. 17, n. 11, 1 jun. 2020. DURMUŞ İSKENDER, M.; ÇALIŞKAN, N. Effect of Acupressure and Abdominal Massage on Constipation in Patients with Total Knee Arthroplasty: A Randomized Controlled Study. Clinical Nursing Research, v. 31, n. 3, p. 453–462, 1 mar. 2022. ERDRICH, L. M.; REID, D.; MASON, J. Does a manual therapy approach improve the symptoms of functional constipation? A systematic review of the literature. International Journal of Osteopathic MedicineElsevier Ltd, , 1 jun. 2020. FAGHIHI, A.; ZOHALINEZHAD, M. E.; NAJAFI KALYANI, M. Comparison of the Effects of Abdominal Massage and Oral Administration of Sweet Almond Oil on Constipation and Quality of Life among Elderly Individuals: A Single-Blind Clinical Trial. BioMed Research International, v. 2022, 2022. FEKRI, Z. et al. The effects of abdominal “I LOV U” massage along with lifestyle training on constipation and distension in the elderly with stroke. Complementary Therapies in Medicine, v. 57, 1 mar. 2021. FOROOTAN, M.; BAGHERI, N.; DARVISHI, M. Chronic constipation. Medicine (United States)Lippincott Williams and Wilkins, , 1 maio 2018. GANESH, S.; KUMAR, M. Physiotherapist management of a patient with spastic perineal syndrome and subsequent constipation: a case report. Physiotherapy Theory and Practice, v. 37, n. 1, p. 242–251, 2021. GARCIA, L. B. et al. CONSTIPAÇÃO INTESTINAL: ASPECTOS EPIDEMIOLÓGICOS E CLÍNICOS. Revista Saúde e Pesquisa, v. 9, n. 1, p. 153–162, 2016. GU, X. et al. Analysis of the efficacy of abdominal massage on functional constipation: A meta-analysis. Heliyon, v. 9, n. 7, 1 jul. 2023. GÜRSEN, C. et al. Effect of Connective Tissue Manipulation on Symptoms and Quality of Life in Patients with Chronic Constipation: A Randomized Controlled Trial. Journal of Manipulative and Physiological Therapeutics, v. 38, n. 5, p. 335–343, 1 jun. 2015. GÜVEN, Ş. D. Improving Quality of Life in The constipated Older Person. Gastroenterology Nursing, v. 46, n. 6, p. 445–454, 1 nov. 2023. HANAI, A. et al. Effects of a self-management program on antiemetic-induced constipation during chemotherapy among breast cancer patients: a randomized controlled clinical trial. Breast Cancer Research and Treatment, v. 155, n. 1, p. 99–107, 1 jan. 2016. HEITMANN, P. T. et al. Understanding the physiology of human defaecation and disorders of continence and evacuation. Nature Reviews Gastroenterology and HepatologyNature Research, , 1 nov. 2021. 60 HUANG, S. Y.; CHIAO, C. Y.; CHIEN, L. Y. Effectiveness of abdominal massage on chronic constipation in adults: A systematic review and meta-analysis. International Journal of Nursing StudiesElsevier Ltd, , 1 jan. 2025. INKAYA, B.; TUZER, H. Effect of reflexology on the constipation status of elderly people. Yonago Acta Medica, v. 63, n. 2, p. 115–121, 2020. JEON SY, J. H. The effects of abdominal meridian massage on constipation among CVA patients. Taehan Kanho Hakhoe Chi, v. 35(1), p. 135–42, 2005. JEONG, S. Y.; JUNG, H. M. The Effects of Abdominal Meridian Massage on Constipation among CVA Patients. Journal of Korean Academy of Nursing, v. 35, n. 1, p. 135, 2005. JOSHI, S. et al. Effectiveness of structured physiotherapy in constipation in children with neurodevelopmental disorders–a randomized trial. Physiotherapy Theory and Practice, v. 40, n. 1, p. 2–10, 2024. KIRCA, A. Ş.; KANZA GÜL, D. Effects of self-acupressure on pregnancy-related constipation: A single-blind randomized controlled study. Explore, v. 17, n. 5, p. 463–468, 1 set. 2021. LACY, B. E. et al. Bowel disorders. Gastroenterology, v. 150, n. 6, p. 1393- 1407.e5, 1 maio 2016. LAI, T. K. T. et al. Effectiveness of aroma massage on advanced cancer patients with constipation: A pilot study. Complementary Therapies in Clinical Practice, v. 17, n. 1, p. 37–43, fev. 2011. LEE, J. et al. Effects of Foot Reflexology on Fatigue, Sleep and Pain: A Systematic Review and Meta-analysis. Journal of Korean Academy of Nursing, v. 41, n. 6, p. 821, 2011. MCCLURG, D. et al. Abdominal massage for the alleviation of constipation symptoms in people with multiple sclerosis: A randomized controlled feasibility study. Multiple Sclerosis Journal, v. 17, n. 2, p. 223–233, 2011. MCCLURG, D. et al. Abdominal massage for the alleviation of symptoms of constipation in people with Parkinson’s: A randomised controlled pilot study. Age and Ageing, v. 45, n. 2, p. 299–303, 1 mar. 2016. MCCLURG, D. et al. Abdominal massage plus advice, compared with advice only, for neurogenic bowel dysfunction in MS: A RCT. Health Technology Assessment, v. 22, n. 58, p. 1–133, 1 out. 2018. NASCIMENTO, M.; TRIPPO, K. Técnicas de terapias manuais no manejo da constipação por trânsito colônico lento e por defecação dissinérgica – protocolo para revisão sistemática com metanálise. Revista de Medicina, v. 103, n. 6, 27 jan. 2025. 61 NIEH, H. C. et al. Effect of acupressure on alleviating constipation among inpatients with stroke during the acute phase: A randomized controlled trial. Complementary Therapies in Clinical Practice, v. 53, 1 nov. 2023. NOUHI, E. et al. The effect of abdominal massage on the severity of constipation in elderly patients hospitalized with fractures: A randomized clinical trial. International Journal of Orthopaedic and Trauma Nursing, v. 47, 1 nov. 2022. OLGUN, S.; ESER, I.; OLĞUN, S. The Effect of Abdominal Massage on Chronic Constipation and Constipation Quality of Life in Elderly: A Randomized Controlled Trial Corresponding AuthorInternational Journal of Caring Sciences. [s.l: s.n.]. Disponível em: <www.internationaljournalofcaringsciences.org>. ORHAN, C. et al. The effects of connective tissue manipulation and Kinesio Taping on chronic constipation in children with cerebral palsy: a randomized controlled trial. Disability and Rehabilitation, v. 40, n. 1, p. 10–20, 2 jan. 2018. PAGE, M. J. et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. The BMJBMJ Publishing Group, , 29 mar. 2021. PASIN NETO, H.; BORGES, R. A. Visceral Mobilization and Functional Constipation in Stroke Survivors: A Randomized, Controlled, Double-Blind, Clinical Trial. Cureus, 11 maio 2020. PRICHARD, D. O.; BHARUCHA, A. E. Recent advances in understanding and managing chronic constipation. F1000ResearchF1000 Research Ltd, , 2018. RAO, S. S. C. Constipation: Evaluation and Treatment of Colonic and Anorectal Motility Disorders. Gastroenterology Clinics of North America, set. 2007. RAO, S. S. C. Constipation: Evaluation and Treatment of Colonic and Anorectal Motility Disorders. Gastrointestinal Endoscopy Clinics of North America, jan. 2009. ROQUE, M. V.; BOURAS, E. P. Epidemiology and management of chronic constipation in elderly patients. Clinical Interventions in AgingDove Medical Press Ltd., , 2 jun. 2015. SAJADI, M. et al. The effect of foot reflexology on constipation and quality of life in patients with multiple sclerosis. A randomized controlled trial. Complementary Therapies in Medicine, v. 48, 1 jan. 2020a. SAJADI, M. et al. The effect of foot reflexology on constipation and quality of life in patients with multiple sclerosis. A randomized controlled trial. Complementary Therapies in Medicine, v. 48, 1 jan. 2020b. SCOTT, S. M. et al. Chronic constipation in adults: Contemporary perspectives and clinical challenges. 1: Epidemiology, diagnosis, clinical associations, pathophysiology and investigation. Neurogastroenterology and MotilityJohn Wiley and Sons Inc, , 1 jun. 2021a. 62 SCOTT, S. M. et al. Chronic constipation in adults: Contemporary perspectives and clinical challenges. 1: Epidemiology, diagnosis, clinical associations, pathophysiology and investigation. Neurogastroenterology and MotilityJohn Wiley and Sons Inc, , 1 jun. 2021b. SCOTT, S. M. et al. Chronic constipation in adults: Contemporary perspectives and clinical challenges. 1: Epidemiology, diagnosis, clinical associations, pathophysiology and investigation. Neurogastroenterology and MotilityJohn Wiley and Sons Inc, , 1 jun. 2021c. SHARMA, A. et al. Dyssynergic Defecation and Other Evacuation Disorders. Gastroenterology Clinics of North AmericaW.B. Saunders, , 1 mar. 2022. SMITH, A. R. Manual therapy: The historical, current, and future role in the treatment of pain. TheScientificWorldJournal, 2 fev. 2007. SONG, G. et al. Transcutaneous electrical stimulation for gastrointestinal motility disorders. Neurogastroenterology and MotilityJohn Wiley and Sons Inc, , 1 nov. 2023. TARSUSLU, T. et al. The Effects of Osteopathic Treatment on Constipation in Children With Cerebral Palsy: A Pilot Study. Journal of Manipulative and Physiological Therapeutics, v. 32, n. 8, p. 648–653, out. 2009. TURAN, N.; ASTI, T. A. The effect of abdominal massage on constipation and quality of life. Gastroenterology Nursing, v. 39, n. 1, p. 48–59, 28 jan. 2016. VRIESMAN MANA H et al. Management of functional constipation in children and adults. Nature Reviews Gastroenterology and HepatologyNature Research, , 1 jan. 2020. WANG, G. et al. Abdominal massage: A review of clinical and experimental studies from 1990 to 2021. Complementary Therapies in MedicineChurchill Livingstone, , 1 nov. 2022. YAN, L. et al. Effect of traditional Chinese medicine external therapy for functional constipation: a meta-analysisAm J Transl Res. [s.l: s.n.]. Disponível em: <www.ajtr.org>. YILDIRIM, D.; CAN, G.; KÖKNEL TALU, G. The efficacy of abdominal massage in managing opioid-induced constipation. European Journal of Oncology Nursing, v. 41, p. 110–119, 1 ago. 2019. YILDIRIM, D.; KOCATEPE, V.; TALU, G. K. The efficacy of acupressure in managing opioid-induced constipation in patients with cancer: A single-blind randomized controlled trial. Supportive Care in Cancer, v. 30, n. 6, p. 5201–5210, 1 jun. 2022. | pt_BR |
| dc.type.degree | Mestrado Acadêmico | pt_BR |
| Aparece nas coleções: | Dissertação (PPGREAB) | |
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