Caracterização química e de atividades biológicas dos óleos fixos de Carpotroche brasiliensis e Elaeocarpus serratus com finalidade farmacêutica e cosmética

Abstract

Medicinal plants are sources of several biologically active compounds serving as raw materials for herbal medicines and other medicines. This research carried out chemical and biological prospecting of the species Carpotroche brasiliensis and Elaeocarpus serratus, occurring in Bahia, with the aim of obtaining bioactive fixed and essential oils with biotechnological and cosmetic applications. The species C. brasiliensis belonging to the Achariaceae family has an oil extracted from the seed qith insecticidal and antiparasitic actions and E. serratus is recognized for its antimicrobial action and is used in the treatment of diarrhea, rheumatism and hair growt, these species being found in northeastern Brazil, particularly in Bahia. The oils were obtained through extraction methods for fixed oils such as maceration, Soxhlet and for essential oils Clevenger and evaluated through tests for antioxidant, cytotoxic, antimicrobial and pediculicidal activity. The compositions of the oils were determined by direct injection gas chromatography, infrared, thermal analysis. Bioactive oils have been subjected to the development of emulsified systems that can improve the biological availability of active substances. The galenic formulas obtained were also evaluated by physicochemical methods of accelerated stability such as vortex exposure, centrifugation, in addition to monitoring pH and organoleptic properties. Spreadability and viscosity tests were also carried out. In this way, the research identified the obtaining of fixed oils and innovative pharmaceutical and cosmetic products with pediculicidal properties, low values for acidity and high for the saponification index as well as the presence of palmitic acid, demonstrating potential food use of the oil from the seed of the E. serratus, oleic acid as a good natural emollient, helping skin permeability. In addition to contributing to the functionality, chemical and biological knowledge of plant species in Bahia.