Avaliação de uma onda folicular em cabras naturalmente infectadas por Corynebacterium Pseudotuberculosis

Abstract

Costa, L. N. F. Evaluation of a follicular wave in goats naturally infected with Corynebacterium pseudotuberculosis. Salvador, 2021. 51p. Dissertation (Mestrado em Ciência Animal nos Trópicos) ± Escola de Medicina Veterinária e Zootecnia ± Universidade Federal da Bahia, 2021. Caseous lymphadenitis is a chronic disease, characterized by the presence of abscesses in the lymph nodes and organs of farm animals, and its etiologic agent is Corynebacterium pseudotuberculosis. Transmission occurs mainly through direct contact between animals carrying the disease and healthy ones. Control measures are vaccination and isolation of infected animals. As a result of this pathology, there is a reduction in the productive and reproductive rates of animals. Based on this information, this study aimed to evaluate the follicular wave of goats naturally infected with C. pseudotuberculosis. Therefore, twenty-one goat females, crossbred, non-pregnant and of reproductive age, previously selected through ELISA test to define the four experimental groups formed by seropositive and seronegative goats, submitted or not to the pharmacological control of the estrous cycle. On a random day of the estrous cycle, called day zero (D0), a cycle synchronization protocol was started to assess ovarian dynamics, through the intravaginal insertion of a progesterone device. On day nine (D9) the device was removed along with the application of 300UI Rf eCG aQd 125ȝg Rf cORSURVWeQRO in all animals in the treatment group, by intramuscular route. Then, to monitor the follicular dynamics, the females underwent transrectal ultrasound examination, in B-mode and power flow, every 12 hours, from the zero hour of implant removal until 72 hours later, totaling five evaluations , to measure follicular diameter, ovulatory follicle diameter, follicular growth rate from D9 to day eleven, follicular wall area and follicular wall blood perfusion area, and time between progesterone device removal and ovulation . For the control group, the females had the estrous cycle synchronized only using progesterone implant, to mimic the natural cycle during the dynamic evaluations. After the analysis, it was found that there were no statistical differences for the variables evaluated, but a trend of seropositive females to have larger diameters of ovulatory follicles. These results assume that the bacterium does not exert influence on the recruitment and initial follicular development of goats submitted to pharmacological control of the estrous cycle, nor on the irrigation area of the follicle wall, indicating that there is no difference in blood perfusion in the evaluated animals.